The gonadotrophins are an interesting group of hormones in which to study relationships of structure with function. They are glycoproteins with carbohydrate components which confer important properties of biological activity and they consist of subunits which bear interesting relationships with one another. Furthermore, they are easier to study than some other hormones because of the specific b...

with prolactin on the maintenance of pregnancy in the rat . . . . . . . . . . . . . . . . . . . . 173 Frdand A., Frandsen V . Aa. and Johnsen S . G.: Adrenal and gonadal contribution to androgen and oestrogen excretion in Klinefelter's syndrome ................ 182 Nielsen J. and Johnsen S. G.: Pituitary gonadotrophins and 17-ketosteroids in patients with the XYY syndrome . . . . . . . . . . . ...

This is a case of partial hypopituitarism resulting from surgery and radiation for a non- functioning pituitary macroadenoma. The patient had amenorrhea which was secondary to hypogonadotrophic hypogonadism and had been on L-thyroxine for central hypothyroidism. For pregnancy, ovulation was induced by gonadotrophins and this was followed by an intrauterine insemination. The antenatal period was...

Prenatal events such as intrauterine growth restriction can affect gonadal development of the offspring and have an impact on reproductive health. To investigate the effects of intrauterine growth restriction induced by uterine artery ligation on the postnatal rat testis. Pregnant rats underwent uterine artery ligation at day 19 of gestation. Offspring were killed at 5, 20 and 40 days post-part...

Whether recombinant gonadotrophin products do, indeed, represent progress for routine ovulation induction and IVF cycles, in comparison with urinary products, has remained controversial. Here we review published data with regard to respective risks, outcomes and cost for both medication options. Safety considerations favour recombinant products, while overall outcome and cost considerations fav...