Lifetime treatment with oral captopril prevents the development of hypertension in spontaneously hypertensive rats (SHR). We tested the hypothesis that this treatment also prevents the hypertensive response that occurs when untreated NaCl-sensitive SHR are placed on a high NaCl diet. Female SHR were continuously treated with oral captopril before conception and throughout lactation, and the off...

KOTCHEN,THEODORE A., JOHN H. GALLA, AND ROBERT G. LUKE. Failure of NaHCO, and KHCO, to inhibit renin in the rat. Am. J. Physiol. 231(4): 1050-1056. 1976. -To evaluate the contribution of chloride to NaCland KCl-induced renin inhibition, renin responses to NaCl or NaHCO, and to KC1 or KHCO, loading were compared in NaCl-deprived rats. Sodium balance in animals drinking isotonic NaHCO, and NaCl f...

This study examined the relationship between NaCl sensitivity and stress response of Listeria monocytogenes. Nine strains of L. monocytogenes (NCCP10805, NCCP10806, NCCP10807, NCCP10808, NCCP10809, NCCP10810, NCCP10811, NCCP10920 and NCCP 10943) were exposed to 0%, 1%, 2% and 4% NaCl, and then incubated at 60℃ for 60 min to select strains that were heat-sensitized (HS) and non-sensitized (NS) b...

Glycosaminoglycans (GAG) of bovine cornea were sequentially extracted by 0.15 M NaCl and by 1 M CaCl2, pH 8. The amounts of hexosamine (HexN) and hexuronic acid (HexUA), specific hexoses (Hex), and protein were determined in the extracts. The ultrastructure of the corneal stroma after NaCl and NaCl/CaCl2 extraction was also studied. Approximately 70% of the Hex-HexN extractable by 0.15 M NaCl i...

Previous results from our laboratory have shown that in the isolated perfused juxtaglomerular apparatus, nonselective inhibitors of cyclooxygenase (COX) activity prevent the stimulation of renin secretion by a reduction in luminal NaCl concentration at the macula densa. The present studies were performed to examine which COX isoform is involved in NaCl-dependent renin secretion. In the absence ...

NaCl and KCl are monovalent salts that can be discriminated behaviorally by hamsters on the basis of their tastes. We examined the effects of the passive Na+ channel blocker amiloride on responses to both of these salts in 34 taste-responsive neurons of the nucleus of the solitary tract (NST) in the hamster. The effects of amiloride were assessed with two different, commonly employed stimulus p...

The effects of increasing NaCl concentrations on biomass, superoxide dismutase (SOD), peroxidase (POD), catalase (CAT), and phenylalanine ammonia-lyase (PAL) in Jatropha curcas L. seedlings were investigated. The fresh weights of cotyledons and radicles with increasing NaCl concentrations decreased progressively, and the fresh weight of hypocotyls reached the lowest level at NaCl concentration ...

The effects of Ca(NO3)2, KF and okadaic acid (OA) on cell hydraulic responses to NaCl were examined in roots of Arabidopsis thaliana wild-type plants and compared with plants overexpressing plasma membrane intrinsic protein PIP2;5. Root treatment with 10 mM NaCl rapidly and sharply reduced cell hydraulic conductivity (L(p)) in the wild-type Arabidopsis plants, but had no effect on L(p) in Arabi...

Aerosolized nanoparticles of NaCl coated with variable amounts of surfactant AOT were generated by electrospraying AOT/NaCl aqueous solutions, followed by neutralizing and drying the resulting particles. A tandem differential mobility analyzer was used to select a narrow size distribution of particles with mobility equivalent diameters below 20 nm and monitor their hygroscopic growth as a funct...

The amiloride-sensitivity of perceived taste qualities and time-intensity patterns for NaCl, and interactions between amiloride and NaCl as taste stimuli, were explored using caffeine as the control treatment. NaCl at 100, 250 and 500 mM, dissolved in 10 or 100 microM amiloride, or in caffeine concentrations matched to the amiloride taste, was flowed over 39.3 mm2 of the anterodorsal tongue for...