Co-morbidity is frequently experienced by gout patients (1) but psychological morbidity associated with gout remains poorly understood. Given the established association between musculoskeletal pain and mental health problems (2), it seems plausible that gout is associated with psychological co-morbidity, such as anxiety or depression. However, the incidence of these specific psychological co-m...

Sickle cell anaemia coexisting with gout is a rare clinical association, as is gout and eosinophilia. This report records the second case of chronic tophaceous deposits in Sickle cell anaemia. The patient also had eosinophilia in association with gout. Skeletal fluorosis was an incidental finding in this patient. Treatment with packed cell transfusions, hydroxyurea and colchicine lead to the re...

Hyperuricemia and gout are two of the most common metabolic diseases in industrial countries. The exacerbated forms of uricemia are the acute gout attack and chronic gout. They are caused by the incorporation of crystalloid salts of uric acid (urate) into the joints. In the following article, we will present all relevant facts concerning gout. This way, you are perfectly prepared for all exams ...

Hyperuricemia and gout are two of the most common metabolic diseases in industrial countries. The exacerbated forms of uricemia are the acute gout attack and chronic gout. They are caused by the incorporation of crystalloid salts of uric acid (urate) into the joints. In the following article, we will present all relevant facts concerning gout. This way, you are perfectly prepared for all exams ...

Refractory gout attack is an uncommon problem, since gout flares are usually self-limited. This clinical condition is characterized by serum uric acid higher than 6 mg/Dl or continuous manifestations of recurrent flares, chronic arthritis, and increased tophi. We report in this paper a 69-year-old man with a polyarticular and protracted gout attack, despite usual treatment and low urate sera le...

Gout is a common metabolic disease but spinal gout is rare. We report a case of gouty arthritis affecting the thoracic spine in a 76-year-old male patient with a long history of tophaceous gout who presented with bilateral lower limb weakness. Magnetic resonance imaging of his thoracic spine revealed erosions in the left pedicles of T8 and T10. The initial imaging diagnosis was metastatic disea...

Gout is a common disorder characterized by chronic hyperuricemia and recurrent attacks of acute inflammatory arthritis, affecting approximately 1–3% of the population. Recently, gout has received increased attention partly owing to the development of new therapies (including the first approved gout treatment in more than 40 years) and an improved understanding of its pathophysiology. Recent res...

Gout affects 1% to 2% of the population, and the prevalence is increasing due to changes in diet and the ageing of the population. Its development and risk factors have been explored frequently, and recommendations for the diagnosis and management of gout implemented. Nevertheless, there is a lack of knowledge regarding the long-term impact on gouty patients. This systematic review therefore ev...

The definitive classification or diagnosis of gout normally relies upon the identification of MSU crystals in SF or from tophi. Where microscopic examination of SF is not available or is impractical, the best approach may differ depending upon the context. For many types of research, clinical classification criteria are necessary. The increasing prevalence of gout, advances in therapeutics and ...

Gout is a systemic, inf lammatory arthritis caused by deposition of monosodium urate (MSU) crystals within synovial or periarticular tissue. Currently, it is estimated to affect 6.1 million Americans [1,2]. The acute phase of gout manifests clinically as a monoarticular inflammatory arthritis, and can mimic a septic joint. Chronic gout is characterized by the formation of tophi, both intraosseo...