The objective of this study was to measure outcomes and to determine the safety and effectiveness of mild induced hypothermia in children after traumatic and posthypoxic brain injury. Methods. Forty patients, following traumatic or posthypoxic brain injury, were involved in the study. Mean age was 10.7 ± 0.8 years. Median GCS (Glasgow Coma Scale) was 6.0 (4-7) and mean PIM2 (Pediatric Index of ...

Faecal microbial changes associated with ageing include reduced bifidobacteria numbers. These changes coincide with an increased risk of disease development. Prebiotics have been observed to increase bifidobacteria numbers within humans. The present study aimed to determine if prebiotic galacto-oligosaccharides (GOS) could benefit a population of men and women of 50 years and above, through mod...

Phenols (phenol and p-cresol) are amino acid metabolites produced by intestinal bacteria. Some reports have demonstrated that the accumulation of phenols in the serum has toxic effects in renal failure patients. In this study, we found that phenols accumulated in the serum of rats given a tyrosine diet, and that dietary intake of a galacto-oligosaccharide mixture (GOS) suppressed the accumulati...

In a balanced incomplete block design, two dry Holstein cows were used to investigate the effect of β 1-4 galactooligosaccharides (GOS) supplementation on nitrogen (N) utilization, rumen fermentation and microbial N supply in the rumen. During the experiment, cows were fed four diets: orchardgrass (Dactylis glomerata L.) silage (OS), OS with GOS supplementation (OSG), OS mixed with alfalfa (Med...

BACKGROUND To ensure the suitability of an infant formula as the sole source of nutrition or provide benefits similar to outcomes in breastfed infants, advancements in formula composition are warranted as more research detailing the nutrient composition of human milk becomes available. This study was designed to evaluate growth and tolerance in healthy infants who received one of two investigat...

OBJECTIVE To present the results of cerebral aneurysms treated by endovascular technique. METHOD Retrospective analysis of patient files of Hospital Geral de Fortaleza, Brazil. RESULTS We report the results of 163 cerebral aneurysms treated by endovascular techniques from January 2002 to October 2005. Patients with ruptured aneurysms (87.2%), according to Hunt-Hess scale were: 33.7% HH I, 2...

Galactosyl-oligosaccharides (GOS) can be produced with native enzymes in Continuous Recycle Membrane Reactors (CRMR) or with immobilized enzymes in Plug Flow Bed Reactors (PFBR). In this paper a simple three kinetic constants model was implemented and used to define the optimal operation conditions to obtain a higher GOS yield. Experimental GOS yield and productivity obtained with CRMR were in ...

The Glasgow Outcome Scale (GOS) is firmly established as the primary outcome measure for use in Phase III trials of interventions in traumatic brain injury (TBI). However, the GOS has been criticized for its lack of sensitivity to detect small but clinically relevant changes in outcome. The Glasgow Outcome Scale-Extended (GOSE) potentially addresses this criticism, and in this study we estimate...

BACKGROUND Neurological abnormalities are a key factor in the prognosis of patients with post-cardiac arrest syndrome. In this study, we evaluated whether differences in CT measurements expressed in Hounsfield units (HUs) of the cerebral cortex and white matter can be used as early predictors of neurological outcome in patients treated with hypothermia therapy after hypoxic-ischemic brain damag...

Gate Oxide Short defects are becoming predominant as technology is scaling down. Boolean and IDDQ testing of this defect has been widely studied but there is no paper dedicated to delay testing of this defect. So, this paper studies the delay behavior of Gate Oxide Short faults due to pinhole in the gate oxide. The objective of this paper is to give a detailed analysis of the behavior of the GO...