The evolution and spread of antibiotic resistance, as well as the evolution of new strains of disease causing agents, is of great concern to the global health community. Our ability to effectively treat disease is dependent on the development of new pharmaceuticals, and one potential source of novel drugs is traditional medicine (Frey and Ryan, 2010). The use of traditional medicine to treat in...

Acne is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules) and no inflammatory (comedones, open and closed) lesions. Propionibacterium acnes and Staphylococcus epidermidis are common pus-forming microbes responsible for the development of various forms of, acne vulgaris....

Nanophytomedicines are prepared from active phytoconstituents or standardized extracts. The world market for nanomedicine is estimated to reach $130.9 billion by the fiscal year 2016. Liposome nanoparticle (NP) with entrapped doxorubicin has been reported to be 300 fold more effective because of better pharmacokinetic ability in treatment of Kaposi sarcoma. NP of paclitaxel is used in the treat...

Six rare naturally occurring indazole-type alkaloids including two new compounds, 17-O-(β-d-glucopyranosyl)-4-O-methylnigellidine (1) and nigelanoid (2), and four known compounds (3-6) were isolated from a defatted extract of Nigella sativa (black cumin) seeds. 17-O-(β-d-Glucopyranosyl)-4-O-methylnigellidine (1) increased glucose consumption by liver hepatocytes (HepG2 cells) through activation...

Background: Cuminum cyminum (Cumin) and Curcuma longa (Turmeric) are plant derived spices which are commonly used as a part of everyday recipes in variety of cuisines. They are known causes of platelet dysfunction but Thrombotic thrombocytopenic purpura (TTP) following their consumption has never been reported in the literature. Primary cardiac involvement in TTP is a rare but fatal complicatio...

this study was carried out to evaluate the effect of different levels of essential oils of wormwood (artemisia absinthium) and cumin (cuminum cyminum (on antioxidant status, lipid peroxidation and serum metabolites in broiler chickens for 42 days. 336 day-old male broiler chicks (ross 308) were allocated to 7 treatments with 4 replications .dietary treatments were included a corn-soybean based ...

selection of an appropriate model is important for quantifying response of germination rate to temperature and determination of cardinal temperatures. this study was done to evaluate different nonlinear regression models to describe response of germination rate to temperature in medicinal pumpkin, borago and black cumin. the regression models were dent-like, segmented, beta, curvilinear, quadra...

to introduce ecologically safe acaricide, effects of essential oils derived from cuminum cyminum (cumin), syzygium aromaticum (clove), and mentha spicata (spearmint) were determined on tetranychus urticae at 25±1◦c, 65±5% rh and a photoperiod of 16:8 (l:d) hour. the essential oils extracted by hydro-distillation were characterized by means of gc and gc–ms. bioassays were performed by filter pap...