Significant excursion of the ulnar nerve is required for unimpeded upper extremity motion. This study evaluated the excursion necessary to accommodate common motions of daily living and associated strain on the ulnar nerve. The 2 most common sites of nerve entrapment, the cubital tunnel and the entrance of Guyon's canal, were studied. Five fresh-frozen, thawed transthoracic cadaver specimens (1...

A null mutation was introduced into the mouse desmin gene by homologous recombination. The desmin knockout mice (Des -/-) develop normally and are fertile. However, defects were observed after birth in skeletal, smooth, and cardiac muscles (Li, Z., E. Colucci-Guyon, M. Pincon-Raymond, M. Mericskay, S. Pournin, D. Paulin, and C. Babinet. 1996. Dev. Biol. 175:362-366; Milner, D.J., G. Weitzer, D....

Scoring systems are classification models that make predictions using a sparse linear combination of variables with integer coefficients. Such systems are frequently used in medicine because they are interpretable; that is, they only require users to add, subtract and multiply a few meaningful numbers in order to make a prediction. See, for instance, these commonly used scoring systems: (Gage e...

OBJECTIVES This study aims to report our experience regarding patients who were surgically treated due to hypothenar hammer syndrome and review the related literature. PATIENTS AND METHODS The study included 11 hands of eight patients (5 males, 3 females; mean age 48 years; range 29 to 60 years) who underwent surgery due to hypothenar hammer syndrome between September 2004 and March 2013. Mea...

Although the performance of current automatic recognition algorithms of on-line handwriting has much improved in recent years, there are still many problems with the actual application of these systems. It appears that the step from academical experiments to real-life use of such algorithms, in, e.g., portable pen computers, is still difficult. What is particularly intriguing is the fact that r...

In 1836, Mercier first vigorously called attention to the occasional occurrence of obstructions at the prostatic orifice in cases other than prostatic hypertrophy, and gave them the name of valvules du col de la vessie. He described quite accurately the elevation of the median portion of the prostate in the form of a bar, which he said in some cases was due to muscular hypertrophy, and in other...

and knowledge they shared during this project. Finally, I would like to thank my parents, Dr. Guy and Norma McCormack as well as my brother Guyon for continuing support in my academic endeavors. Table Page 1. Timepoints at which significant changes in histological and hyperspectral endpoints were measured with trastuzumab treatment in BT474 and HR6 xenografts……………….…….27 6: Tumor response in tr...