AbstractObjectives Previous studies have shown low to moderate evidence for a variety of magnetic resonance imaging (MRI) features as prognostic factors in athletes with hamstring injuries. Short-tau inversion recovery (STIR) signal intensity has not yet been investigated assessing the prognosis acute muscle Our aim was explore relationship between MRI STIR and time return pla...

Abstract Objective To determine the continuity of care (CoC) provided by general practitioners among workers with low back pain; identify personal, workplace and social factors associated CoC in this population; investigate if is working time loss. Data sources An administrative database containing accepted workers’ compensation claim service level data, for pain from...

Context: Tapering of long-term opioid therapy (LTOT) increased after publication the 2016 CDC guidelines, followed by anecdotal reports exacerbated pain among tapered patients. However, two systematic reviews limited evidence from multidisciplinary control programs found similar or better ratings tapering versus baseline. Objective: To evaluate association between dose and sub...

Context: Digital therapeutics may be uniquely positioned to address challenges reported by providers in chronic pain (CP) management. Previous studies have shown patient-provider discordance priorities for CP management, which can addressed digital development encourage implementation and use. Objective: To assess primary care providers’ patients’ perceptions of treatment goal...

In the present paper we report the genomic organization of the human histamine H3-receptor gene, which consists of four exons spanning 5.5 kb on chromosome 20. Using PCR, six alternative splice variants of the H3 receptor were cloned from human thalamus. These variants were found to be coexpressed in human brain, but their relative distribution varied in a region-specific manner. These isoforms...

Introduction Text messaging is an effective way to reach large populations with health promotion support. This study aims establish the optimal text intervention achieve behavior change in young adults at risk of skin cancer. Study Design Latin square crossover RCT. Setting/participants Participants were women and men aged 18–40 years living Queensland, Australia who ...

B7-H3, a recently identified B7 family member, has different isoforms in human and mouse. Mouse B7-H3 gene has only one isoform (2IgB7-H3) with two Ig-like domains, whereas human B7-H3 has two isoforms (2IgB7-H3 and 4IgB7-H3). In this study a systematic genomic survey across various species from teleost fishes to mammals revealed that 4IgB7-H3 isoform also appeared in pigs, guinea pigs, cows, d...

Context: Frailty is a state in which physiological reserve depleted across multiple systems, leading to an increased risk of decompensation response stressor events. factor for dementia and complicates its management. However, frailty rarely reported clinical trials mild cognitive impairment (MCI) limits assessment trial applicability. Objective: This analysis will assess the ...