نتایج جستجو برای: h5n1
تعداد نتایج: 4735 فیلتر نتایج به سال:
Since the first recorded infection of humans with H5N1 viruses of avian origin in 1997, sporadic human infections continue to occur with a staggering mortality rate of >60%. Although sustained human-to-human transmission has not occurred yet, there is a growing concern that these H5N1 viruses might acquire this trait and raise the specter of a pandemic. Despite progress in deciphering viral det...
BACKGROUND Active serologic surveillance of H5N1 highly pathogenic avian influenza (HPAI) virus in humans and poultry is critical to control this disease. However, the need for a robust, sensitive and specific serologic test for the rapid detection of antibodies to H5N1 viruses has not been met. METHODOLOGY/PRINCIPAL FINDINGS Previously, we reported a universal epitope (CNTKCQTP) in H5 hemagg...
We describe a 1-step reverse-transcription loop-mediated isothermal amplification assay for detection of highly pathogenic avian influenza A (H5N1) viruses. The assay was tested by using a panel of highly pathogenic H5N1 subtypes isolated over the past 10 years and clinical specimens. The assay produced negative results for all non-H5N1 subtypes.
There is little information about highly pathogenic avian influenza (HPAI) H5N1 virus in Africa, where health infrastructure is inadequate and human–animal contact is common. and [2] The global status of HPAI H5N1 in human beings was recently reported, but region and continent-specific information remains deficient. Here we describe how urbanisation and altered farming have increased the risk o...
Inoculation of influenza (H5N1) into beagles resulted in virus excretion and rapid seroconversion with no disease. Binding studies that used labeled influenza (H5N1) showed virus attachment to higher and lower respiratory tract tissues. Thus, dogs that are subclinically infected with influenza (H5N1) may contribute to virus spread.
in the february 2006 in two wetlands in northern iran, the mortality among wild swans was observed. paralysis was the most prominent feature of the disease. histologically, diffused necrosis of acinar cells in pancreas, degeneration and necrosis of some neurons in central nervous system (cns), sever necrotic and hemorrhagic enteritis, foci of haemorrahge and myocardial cell necrosis in the hear...
زمینه و اهداف: ویروس h5n1 ممکن است قابلیت انتقال بین انسان ها را بدست آورد. بنابراین امکان وقوع یک بیماری همه گیر وجود دارد. پروتئین ha1 نقش اصلی را در اتصال ویروس به سلول هدف بازی می کند و پاسخ های آنتی بادی خنثی کننده عمدتاً علیه این ناحیه است. باسیلوس سوبتیلیس میزبانی بدون اندوتوکسین جهت بیان وترشح پروتئین های هترولوگ واجد فعالیت ایمونولوژیک شناخته شده است. اگر چه این باکتری قادر به تولید پ...
BACKGROUND Early initiation of treatment is essential for treatment of avian influenza A/H5N1 viral infection in humans, as the disease can lead to rapid development of severe pneumonia which can result in death. Contact with infected poultry is known to be a significant risk factor for contraction of H5N1 infection. However, handling and encountering poultry are a part of most peoples' daily l...
UNLABELLED A change in viral hemagglutinin (HA) receptor binding specificity from α2,3- to α2,6-linked sialic acid is necessary for highly pathogenic avian influenza (AI) virus subtype H5N1 to become pandemic. However, details of the human-adaptive change in the H5N1 virus remain unknown. Our database search of H5N1 clade 2.2.1 viruses circulating in Egypt identified multiple HA mutations that ...
BACKGROUND Qinghai Lake in central China has been at the center of debate on whether wild birds play a role in circulation of highly pathogenic avian influenza virus H5N1. In 2005, an unprecedented epizootic at Qinghai Lake killed more than 6000 migratory birds including over 3000 bar-headed geese (Anser indicus). H5N1 subsequently spread to Europe and Africa, and in following years has re-emer...
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