The purpose of this study was to report the characteristics of an equivalent quality unflattened (eqUF) photon beam in clinical implementation and to provide a generalized method to describe unflattened (UF) photon beam profiles. An unflattened photon beam with a beam quality equivalent to the corresponding flat 6 MV photon beam (WF) was obtained by removing the flattening filter from a Siemens...

background: in this study, quantitative 32p bremsstrahlung planar and spect imaging and consequent dose assessment were carried out as a comprehensive phantom study to define an appropriate method for accurate dosimetry in clinical practice. materials and methods: ct, planar and spect bremsstrahlung images of jaszczak phantom containing a known activity of 32p were acquired. in addition, phanto...

A mini-ridge filter is often used to widen the Bragg peak in the longitudinal direction at low energies but not high energies. To facilitate the clinical use of a mini-ridge filter, we performed a planning study for the feasibility of a mini-ridge filter as an integral part of the synchrotron nozzle (IMRF). Dose models with and without IMRF were commissioned in a commercial Treatment planning s...

Measurement of cumulative dose ƒ(0,150) with a small ionization chamber within standard polymethyl methacrylate (PMMA) CT head and body phantoms, 150 mm in length, is a possible practical method for cone-beam computed tomography (CBCT) dosimetry. This differs from evaluating cumulative dose under scatter equilibrium conditions within an infinitely long phantom ƒ(0,∞), which is proposed by AAPM ...

Introduction: In electron beam treatment, because of the non-point electron beam source, inverse-square law cannot be applied for dosimetry in different treatment intervals. Therefore, providing source-surface distance (SSD) charts in all clinics is of paramount importance. This study aimed to determine the effective SSD for various electron beam energies and field sizes and to...

Introduction: One of scientific concern is increasing of unwanted neutron dose to the patient, in head and neck radiation therapy due to the presence of some isotopes in dental restorations and head of medical linac. The aim of this study is to measure the equivalent dose of thermal and fast neutron due to head of Siemens Primus Linac and a healthy tooth, Amalgam, Ni-Cr alloy a...

From the Departments of Ophthalmology, and Neurosciences Division of Research, Medical University of South Carolina, Charleston, SC 29425 Running head: Sublytic MAC alters regulated VEGF secretion # Address correspondence to: Bärbel Rohrer, Department of Ophthalmology, Medical University of South Carolina, 167 Ashley Ave, SEI 511, Charleston SC, 29425. Tel: 843-792-5086; Fax: 843-792-1723; Emai...

Cone-beam computed tomography (CBCT) images suffer from poor image quality, in a large part due to contamination from scattered X-rays. In this work, a Monte Carlo (MC)-based iterative scatter correction algorithm was implemented on measured phantom data acquired from a clinical on-board CBCT scanner. An efficient EGSnrc user code (egs_cbct) was used to transport photons through an uncorrected ...

PURPOSE The consummate 64-slice CT scanner that spawns a new generation of non-invasive diagnostic tool, however revolutionary, brings with it the incidental by-product that is scattered radiation. The extended detector aperture capability in the 64-slcie CT scanner allows the effects of scattered radiation to be more pronounced and therefore demands that the magnitude and spatial distribution ...

OBJECTIVES Combined positron emission tomography (PET) and magnetic resonance imaging (MRI) targeting the prostate-specific membrane antigen (PSMA) with a 68Ga-labelled PSMA-analog (68Ga-PSMA-11) is discussed as a promising diagnostic method for patients with suspicion or history of prostate cancer. One potential drawback of this method are severe photopenic (halo-) artifacts surrounding the bl...