BACKGROUND The recent introduction of operations on a warm heart has prompted clinical reports on the usefulness of continuous blood cardioplegia, but no in-depth basic evaluation of continuous cardioplegia has been done. The cardioprotective effects of magnesium (Mg) and calcium (Ca) in continuous warm hyperkalemic crystalloid cardioplegic solutions were investigated in an isolated rat heart m...

BACKGROUND On-pump beating-heart coronary artery bypass grafting surgery (CABG) is beneficial due to the elimination of cardioplegic arrest. However, there are few reports regarding its efficacy in chronic hemodialysis patients. This study investigated the potential benefits of on-pump beating-heart CABG in chronic hemodialysis patients. METHODS From January 2002 to January 2010, 186 patients...

Background: Cardiopulmonary arrest (CPA) is a severe public health problem and leading cause of death worldwide. According to the American Heart Association (AHA), basic life support (BLS) bedrock for improving people's survival after cardiac arrest, cardiopulmonary resuscitation crucial. Through scientific evidence, empowering professionals focuses on education in vital identify attend CPA vic...

BACKGROUND Resting sympathetic nervous system activity is increased in heart failure. Whether sympathetic nervous system responses during exercise are increased is controversial. Furthermore, the role of muscle metaboreceptors and central command in regulating sympathetic outflow has been largely unexplored. METHODS AND RESULTS Muscle sympathetic nerve activity (MSNA, peroneal nerve) was meas...

To study the effect of halothane as a cardioplegic agent, ten Wistar rats were anesthetized by ether inhalation and their hearts were perfused in a Langendorff system with Krebs-Henseleit solution (36 degrees C; 90 cm H2O pressure). After a 15-min period for stabilization the control values for heart rate, force(T), dT/dt and coronary flow were recorded and a halothane-enriched solution (same t...

Mechanical circulatory support (MCS) for saving infants with severe congenital heart disease who are receiving traditional cardio-pulmonary resuscitation has never been conducted before. The selection of timing and indications of MCS is associated with clinical ethics, and most of the doctors are more cautious in the application of extracorporeal membrane oxygenation (ECMO) for infants with sev...

OUT-OF-HOSPITAL CARDIAC arrest survival remains poor in most jurisdictions more than 30 years after Pantridge and Geddes introduced the concept of providing advanced cardiac life support (ACLS) care to patients with cardiac arrest outside of the hospital setting with mobile intensive care vehicles in Belfast. Reported cardiac arrest survival rates range from 1% to 20%, and this variation can be...

Cardiopulmonary bypass and cardioplegic arrest, which allow for support of the circulation and stabilization of the heart during cardiac procedures, are still used for the vast majority of cardiac operations worldwide. However, in addition to a well-recognized systemic inflammatory response, cardiopulmonary bypass and cardioplegic arrest elicit complex, multifactorial vasomotor disturbances tha...

The aim of the present study is to assess the complications of mild induced hypothermia (MIH) in patients with cardiac arrest. Presently, based on the guidelines of the American heart Association, MIH following successful cardiopulmonary resuscitation (CPR) in unconscious adult patients due to ventricular fibrillation (VF) with out-of-hospital cardiac arrest (OOHCA) is essential and required. H...