THOUGH most patients with secondary neoplastic involvement of the heart or pericardium seem to manifest no symptoms or signs of such involvement, a sizable proportion do have actual impairment of cardiac funetion. Refinements in thoracic, and specifically cardiac, surgery, in roentgen therapy, and in the use of isotopic and chemotherapeutic agents have made definite palliation available for met...

Cancer constitutes a major problem in animal pathology and is a subject of intensive research. Canine mammary tumors are common neoplasms and have been reported to account for up to half of all tumors in female dog [1]. All malignant canine mammary tumors have the potential to metastasize and in general, metastasis tends to occur via the lymphatic system to the inguinal lymph nodes or hematogen...

Primary cardiac tumors are a rare set of benign and malignant neoplasms found in the heart or pericardium. We describe a patient presenting with nonspecific symptoms and ultimately diagnosed with primary cardiac non-Hodgkin's lymphoma (PCL). Our patient had extensive tumor in the right ventricle, which extended into the right atrium and right ventricular outflow tract. The tumor also encased th...

In infants and children, pancreatic neoplasms occur uncommonly. Histologically, these tumors can resemble pancreatic embryonic elements or more well-differentiated pancreatic structures, in a subset the cellular origin can’t be delineated. This review discusses three of the most classic pediatric pancreatic neoplasms: pancreatoblastoma, solid pseudopapillary neoplasms and pancreatic endocrine n...

Biliary (hepatic and extrahepatic) intraductal papillary mucinous neoplasms and intraductal oncocytic papillary neoplasms/carcinoma are rare neoplasms. Classification of biliary intraductal papillary tumors can be confusing and reports in radiology literature are extremely limited. We describe the first reported case of biliary intraductal oncocytic papillary neoplasms/carcinoma in the liver in...

background: early detection and screening have been successful in reducing mortality in some countries, but not in others. this is most of due to poor management and implementation of inappropriate policies. all of patients with cervical cancer are in developing countries. the effectiveness of screening for cancer of the cervix in these countries is dramatic. it seems that after 50 years pap sm...

results like other cancers, prostate cancer is caused by an accumulation of genetic alterations in a cell that drives it to malignant growth. specific genes and gene alterations have been suggested to play a role in its development and progression. aneuploidy, loss of heterozygosity, gene mutations, hypermethylation and inactivation of specific tumour suppressor genes such as gstpi, apc, mdr1, ...

breast cancer is the most common cause of cancer-related death in female, after lung cancer. angiogenesis is essential for tumor growth and metastasis; therefore, antiangiogenesis strategies for treatment of cancer are currently an issue of interest. the role of vascular endothelial growth factor that assumed to be most potent angiogenesis factor is ambiguous in breast cancer. this study descri...

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mirs are 17-25 nucleotide non-coding rnas. these rnas target approximately 80% of protein coding mrnas. mirs control gene expression and altered expression of them affects the development of cancer. mirs can function as tumor suppressor via down-regulation of proto-oncogenes and may function as oncogenes by suppressing tumor suppressors. myeloproliferative neoplasias (formerly known as chronic ...