a2-year-old cachectic cross-breed gelding was admitted toveterinary teaching hospital of university of tehran followingthe onset of a marked respiratory distress, coughing and ventraledema. clinical examinations indicated harsh respiratory andexpiratory sounds as well as jugular vein distention. therespiratory and heart rates were 35/min and 60 bpm, respectively.agrade iii/iv pansystolic murmur...

Senescence is a recognized mechanism of cardiovascular diseases; however, its contribution to myocardial fibrosis and rupture after infarction and the underlying mechanisms remain unclear. Here we showed that senescent cardiac fibroblasts markedly accumulated in heart after myocardial infarction. The expression of key senescence regulators, especially p53, was significantly up-regulated in the ...

are rare cardiac abnormalities. They are dilatations of the aortic sinuses and are classified as congenital or acquired. Sometimes they coexist with other congenital heart diseases and they often rupture into the heart chambers causing acute clinical syndrome. ASVs and coexisting congenital heart disease can easily be diagnosed with echocardiography. Early diagnosis and immediate surgical treat...

Although occurance of sudden and extensive hemorrhage is not a new subject, however due to high morbidity and mortality a high level of experience and expertise is required to control the situation.Single adrenaline injction that is fast and very potent has been used in order to maintain BP and help the use of blood saved in other parts of the body.Durring 1375 to 1381 a total of 8 patients wer...

This paper presents flexible electronics with a bio-compatible material interface for bio-signal monitoring applications. Organic thin-film transistors (TFT) are integrated with the bio-compatible gel interface in a 1.2-μm-thick film substrate. An electrocardiogram (ECG) of a rat is amplified by an organic TFT amplifier circuit that is mounted directly on the surface of the heart. In addition t...

Inadequate healing of myocardial infarction may contribute to local expansion of the infarct, frequently leading to chamber dilation, heart failure, or myocardial rupture. Experimental evidence in mouse models suggests that Factor XIII might play a key role in wound healing, and low persistent values lead to increased incidence of cardiac rupture following myocardial infarction. Here we would l...

BACKGROUND Abnormalities of intracellular calcium handling are widely recognized as a common hallmark of heart failure in animal models and humans. Modifying the interaction of phospholamban (PLB) with the sarcoplasmic reticulum ATPase (SERCA) by PLB mutants improves cardiac function but may also lead to heart failure. In this study we describe the in vivo effects of a new approach to modify th...

there was a turning point in each period of time which human has discovered a new sight about the world and nature order in a way, and then has presented this relation by numeral, artful and industrial language. biourbanism focuses on the urban organism, considering it as a hyper complex system, according to its internal and external dynamics and their mutual interactions. nowadays when it is t...

Autotomy refers to the voluntary shedding of a body part; a renowned example is tail loss among lizards as a response to attempted predation. Although many aspects of lizard tail autotomy have been studied, the detailed morphology and mechanism remains unclear. In the present study, we showed that tail shedding by the Tokay gecko (Gekko gecko) and the associated extracellular matrix (ECM) ruptu...

[1] Falk E. Plaque rupture with severe pre-existing stenosis precipitating coronary thrombosis. Characteristics of coronary athersclerotic plaques underlying fatal occlusive thrombi. Br Heart J 1983; 50: 127–34. [2] Davies MJ, Bland JM, Hangartner JR, Angelini A, Thomas AC . Factors influencing the presence or absence of acute coronary thrombi in sudden ischaemic death. Eur Heart J 1989; 10: 20...