OBJECTIVE To analyze the frequency and prevalence of congenital heart defects in a tertiary care center for children with heart diseases. METHODS We carried out an epidemiological assessment of the first medical visit of 4,538 children in a pediatric hospital from January 1995 to December 1997. All patients with congenital heart defects had their diagnoses confirmed at least on echocardiograp...

Many transport processes in nature take place on substrates, often considered as unidimensional lanes. These unidimensional substrates are typically nonstatic: Affected by a fluctuating environment, they can undergo conformational changes. This is particularly true in biological cells, where the state of the substrate is often coupled to the active motion of macromolecular complexes, such as mo...

the most common congenital diseases in children is congenital heart disease. factors such as environment, genetic, old maternal age during pregnancy, maternal disease and using medicine in pregnancy, prematuritiy, and specific seasons are significant in the prevalence of disease.materials and methods: a cross sectional study was conducted to investigate the status of children with congenital he...

CMR is valuable in the evaluation of congenital heart disease (CHD). Traditional flow imaging sequences involve cardiac and respiratory gating, increasing scan time and susceptibility to arrhythmias. We studied a real-time color-flow CMR system for the detection of flow abnormalities in 13 adults with CHD. All 16 congenital flow abnormalities previously detected by echocardiography were visuali...

[1] Son KH, Choi CH, Park KY, Park CH. Which animal model is proper for evaluation of a muscular ventricular septal defect closure device? Eur J Cardiothorac Surg 2016;49:1295. [2] Lang N, Merkel E, Fuchs F, Schumann D, Klemm D, Kramer F et al. Bacterial nanocellulose as a new patch material for closure of ventricular septal defects in a pig model. Eur J Cardiothorac Surg 2015;47: 1013–21. [3] ...

We present an alternative technique for closing multiple ventricular septal defects difficult to access during surgery. A guidewire is advanced through the right ventricular free wall and through the main apical defect to the left ventricle, and this approach is used to place an Amplatzer device to occlude the ventricular septal defects. The procedure is performed in the beating heart, under in...

BACKGROUND Use of the Amplatzer septal occluder (ASO) for the closure of secundum atrial septal defect (ASD) has recently become the procedure of choice, while earlier the only treatment for ASD was surgical closure. This study compares the right ventricular indices of the ASO group with the surgical closure group one year after intervention in adults. METHODS From January 2008 to February 20...

The families of 26 patients with Ebstein's anomaly were examined. There were 120 first-degree relatives, 100 of whom were living, and 93 of these were examined. Information was available on 14 of the 20 who had died. No case of Ebstein's anomaly was found among the first-degree relatives, but 2 had ventricular septal defects and another, who died at 7 months, was said to have had congenital hea...

Cardiac magnetic resonance imaging (CMR) can provide comprehensive anatomic and physiological information about the cardiovascular system. The review article describes the application of CMR to several simple congenital heart lesions: atrial septal defects and other interatrial communications, ventricular septal defects, patent ductus arteriosus, partially anomalous pulmonary venous connection,...

BACKGROUND The feasibility of fast-tracking children undergoing congenital heart disease surgery has not been assessed adequately. Current knowledge is based on limited single-center experiences without contemporaneous control groups. METHODS AND RESULTS We compared administrative data for atrial septal defect (ASD) and ventricular septal defect (VSD) surgeries in children 2 months to 19 year...