BACKGROUND Helicobacter pylori is one of the most common causes of bacterial infection in human beings. Studies have showed a high prevalence of Helicobacter pylori among people in low-income countries and colonization early in life. A monoclonal antigen test, performed on faeces, HpSA ImmunoCardSTAT, has a high sensitivity, specificity and accuracy and the faecal test can be performed in all a...

AIM It is doubtful that whoever is suffering from gastric malt lymphoma will escape from the disease, if treated with medication against helicobacter pylori. MATERIAL AND METHODS A cohort of 18 patients was analysed. Ten hosts had primary gastric malt lymphoma and were treated with gastric resection as the initial therapy. Eight hosts received antibiotics against Helicobacter pylori as the in...

bismuth salts and different antimicrobials including metonidazole & tetracyclines were used in the assessment of inhibition zone of helicobacter pylori cultures on solid media. antibiotics were used or in combined in order to find out their possible synergistic effects. it was showed that: only bismuth substrate and not then salts have antibacterial effects on helicobacter pylori and also on th...

Helicobacter pylori is associated with an inflammatory reaction in the stomach and duodenum, yet the mechanism of this inflammatory infiltrate is unknown. The ability of Helicobacter pylori to secrete a factor that attracts leucocytes is investigated. Helicobacter pylori conditioned supernatant attracted neutrophils and monocytes with 50-100% of the activity of control chemotactic factor, 10(-8...

background: polymorphisms in the immune related genes are important in the clinical outcome of helicobacter pylori infection. myeloperoxidase -463 g/a polymorphism has been shown to reduce enzyme expression and activity. objective: the aim of the present study is to investigate the association of myeloperoxidase g-463a polymor-phism with clinical outcome of helicobacter pylori infection. method...

helicobacter pylori infection, the most common chronic bacterial infection in the world, and an important cause of gastrointestinal disorders, may be involved in the pathogenesis of some extra-gastrointestinal disturbances, as well as an increase in blood levels of certain inflammatory markers. anti-bacterial activity against helicobacter pylori and anti-inflammatory properties of omega-3 fatty...

Gastric cancer is the third most common cause of cancer-related death in the world. It is now well- established that Helicobacter pylori infection predispose individuals toward gastric adenocarcinoma later in life. It has since been classified as a class I carcinogen by the World Health Organization. Research suggests that the oncogenic effects of Helicobacter pylori can occur through a variety...

PURPOSE Helicobacter pylori colonization of gastric epithelium causes a local and systemic, cellular and humoral immune response. Despite this immune response involvement in the infection, its elimination from the organism does not take place and the process usually becomes chronic. The purpose of the study was to establish the prevalence of gastric mucosa inflammation in children and adults wi...

We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori stra...

BACKGROUND Many of the currently used Helicobacter pylori eradication regimens fail to cure the infection due to either antimicrobial resistance or poor patient compliance. Those patients will remain at risk of developing potentially severe complications of peptic ulcer disease. AIM We studied the impact of the antimicrobial resistance on the efficacy of a short course pantoprazole based trip...