2. Main text, conclusions: Suggest changing first sentence to "In this study, left and right hemispheric foci were associated with discordant psychosocial functioning and QOL scores in children". Is is not correct to say that "Lateralization of epileptic focus can affect psychosocial functioning and lead to diminished QOL in children" as this assumes causation (which cannot be proven based on t...

Hemispheric asymmetry of a wide range of functions is a hallmark of the human brain. The visual system has traditionally been thought of as symmetrically distributed in the brain, but a growing body of evidence has challenged this view. Some highly specific visual tasks have been shown to depend on hemispheric specialization. However, the possible lateralization of cerebral responses to a simpl...

Emotional disturbances in stroke patients may unfavorably affect the process of rehabilitation and longterm outcome of the disease. The aim of the study was to assess the prevalence of emotional disturbances and their characteristics in our stroke patients, according to hemispheric lateralization of cerebral lesion (as recorded by CT), patient sex and grade of neurological handicap (as assessed...

The adult human brain would appear to have specialized and independent neural systems for the visual processing of words and faces. Extensive evidence has demonstrated greater selectivity for written words in the left over right hemisphere, and, conversely, greater selectivity for faces in the right over left hemisphere. This study examines the emergence of these complementary neural profiles, ...

In a widely used decision-making task, the Iowa Gambling Task (IGT), male performance is observed to be superior to that of females, and is attributed to right lateralization (i.e., right hemispheric dominance). It is as yet unknown whether sex-differences in affect and motor lateralization have implications for sex-specific lateralization in the IGT, and specifically, whether sex-difference in...

Developmental dyslexia is a neurological condition characterized by unexpected low reading performance in people with normal intelligence and typical schooling. One prominent theory posits that dyslexic children fail to establish left-hemispheric dominance of visual representations and visual-phonological/meaning integration of printed words and thus exhibit an atypical lateralization of lexica...

What determines the hemispheric laterality of information processing in the human prefrontal cortex (PFC)? Functional neuroimaging studies of declarative memory have explored two proposals: process-specificity and material-specificity. Early studies reported left-lateralized activation in prefrontal regions during memory encoding but right-lateralized activation during memory retrieval, for bot...

In a previous study, N. Cherbuin and C. Brinkman (2006) showed that in right-handed participants, interhemispheric transfer time (measured with A. T. Poffenberger's, 1912, paradigm) was a significant predictor of the efficiency of hemispheric interactions (measured with a split visual field, letter-matching task). No effect was found for degree of handedness in this study. This was surprising b...

Spatial imagery refers to the inspection and evaluation of spatial features (e.g., distance, relative position, configuration) and/or the spatial manipulation (e.g., rotation, shifting, reorienting) of mentally generated visual images. In the past few decades, psychophysical as well as functional brain imaging studies have indicated that any such processing of spatially coded information and/or...