Rationale Atypical hemolytic uremic syndrome, which has a high probability of chronic kidney disease, morbidity, and mortality, needs to be promptly recognized when patients present with microangiopathic hemolysis. Presenting Concerns of the Patient Three patients present with laboratory parameters consistent with a thrombotic microangiopathy. With a suspected diagnosis of thrombotic thromboc...

BACKGRUND Hemolytic uremic syndrome is a disease characterized by hemolytic anemia, thrombocytopenia and acute renal failure with multiple organ involvement. Central nervous system involvement is detected in 20-50% of the patients and this leads to increased morbidity and mortality. CASE REPORT We report the neuroimaging findings in a four-month-old male with hemolytic uremic syndrome. The ce...

BACKGROUND Acute rheumatic fever is a major cause of heart disease in Aboriginal Australians. The epidemiology differs from that observed in regions with temperate climates; streptococcal pharyngitis is reportedly rare, and pyoderma is highly prevalent. A link between pyoderma and acute rheumatic fever has been proposed but is yet to be proven. Group C beta-hemolytic streptococci and group G be...

In discussions of eczema, brief mention is usually made of the fact that superimposed infection often complicates the disease, but one does not gather that the secondary malady is regarded as a factor which may be of prime importance in determining the clinical pattern of the sickness. The parasites may be viruses, fungi, or bacteria and the infection may be single or multiple in etiology. Exam...

We report on a patient affected by multicentric Castleman's disease who developed an acute immunohemolytic anemia due to warm antibody. The clinical course was characterized by refractoriness to the steroidal treatment and by a dramatic improvement of the hematological and objective picture following combination chemotherapy (CHOP regimen). The possible existence of a link between the lymphopro...

KM The primary cause, of course, is maternal antibodies to red blood cells. Their formation usually occurs at delivery, and in the following pregnancy, those antibodies cross through the placenta and can affect the next fetus. When the antibodies attach to the fetal red blood cells, the cells break down and the fetus becomes anemic. In the United States, the 3 antibodies that cause nearly all t...

Sixty-six children with G6PD deficiency were evaluated retrospectively to ascertain the clinical features, etiology, ultimate outcome and population at risk, The occurrence of jaundice in 18 neonates (group J) was, contrary to other countries, in the form of neonatal jaundice type II. Sepsis, prematurity, hypoxia and acidosis were associating factors. 77.8% of neonates had exchange blood t...

Cold agglutinin disease arising in the context of chronic lymphocytic leukemia can misdiagnose a warm autoimmune hemolytic anemia.