BACKGROUND AND PURPOSE Several epidemiological studies have established an association between chronic kidney disease (CKD), based on estimated glomerular filtration rate (GFR), and risk of stroke. However, sex-specific evidence for the relationship between CKD and risk of stroke and its subtypes is still limited. METHODS We conducted a prospective cohort study of 12 222 Japanese men and wome...

C ocaine use is associated with multiple neurovascular complications , including ischemic and hemorrhagic strokes. Intracerebral hemorrhage is especially prevalent in patients with acute cocaine intoxication as defined by positive urine toxin assays. 1 In addition, intracerebral hemorrhage in patients with cocaine intoxication are more severe, often associated with intraventricular hemorrhage, ...

Background and Purpose:Stroke is a devastating major disabling disease affecting 15 million people worldwide per year causing 6 deaths annually (the third leading cause of death after cardiovascular cancer disease). One in six suffers from stroke their lifetime.This study aims to find the clinical profile, risk factors, radiological profile patients Southern Kashmir India. Which will be benefic...

Studies regarding clinical characteristics of stroke involving the posterior circulation territory brain in Bangladesh are rare although large number patients were found hospital admission and with a high morbidity mortality. Study for better understanding features, risk factors aetiologies (PCS) may be very helpful early diagnosis, treatment, also setting primary secondary prevention strategie...

Lacunar strokes result from occlusion of penetrating arteries in the deeper, subcortical parts of the cerebrum and brain stem. Approximately 19 percent of all strokes are of the lacunar variety with lacunar strokes representing the most common cerebrovascular complication of chronic hypertension. Four major clinical syndromes are pure motor hemiparesis, pure sensory stroke, ataxic hemiparesis, ...

Early brain injury (EBI) has become an area of extreme interest in the recent years and seems to be a common denominator in the pathophysiology of global transient ischemia and subarachnoid hemorrhage (SAH). In this paper, we highlight the importance of cerebral hypoperfusion and other mechanisms that occur in tandem in both pathologies and underline their possible roles in triggering brain inj...

BACKGROUND AND PURPOSE Understanding the mechanisms underlying stroke can aid the development of therapies and improve the final outcome. The purposes of this study were to establish whether there are characteristic mechanistic differences in the frequency, severity, functional outcome, and mortality between left- and right-hemisphere ischemic stroke and, given the velocity differences in the c...

Using more than 37,000 hospital discharges attributed to hemorrhagic or occlusive stroke in the province of Quebec, Canada, we analyzed trends in stroke incidence during the period 1981-1988. There were large and statistically significant (p less than 0.05) increases in the rates of hemorrhagic stroke over this period. Dramatic increases occurred among men in the rates of both intracerebral (In...

Stroke is the world's largest neurological defect caused by the disruption of brain blood circulation. Apart from death, the severest damage caused by stroke, a plethora of other mental and physical disabilities can ensue the incidence of a stroke. As a result of the continued disruption of blood circulation triggered by a stroke, biochemical and physiological mechanisms affect nerve cells and ...

Despite advances in pharmacology that have led to increasingly effective antihypertensive drug treatments, the precise pathophysiological mechanisms of hypertension and its complications are still poorly understood. Increasing clinical and laboratory evidence suggests that hypertension per se may confer a prothrombotic or hypercoagulable state.1 This may explain in part why, despite exposure of...