Drug addicts represent a high risk group for acquiring parenterally transmitted viral infections like human immunodeficiency virus (HIV), hepatitis C virus (HCV) and hepatitis B virus (HBV). It is very likely that an injecting drug user (IDU) infected with HIV will also be infected with HBV and/or HCV because of common high risk behaviours. Amritsar being border city, is a seat of international...

Hepatitis C virus (HCV) has become the most significant cause of chronic liver disease of infectious etiology in the United States. The recognition that HCV can be transmitted perinatally or through blood transfusions warrants particular attention by the pediatrician. The American Academy of Pediatrics recommends screening infants born to HCV-infected mothers and persons with risk factors for H...

We carried out a molecular characteristic-based epidemiological survey of various hepatitis viruses, including hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis E virus (HEV), and GB virus C (GBV-C)/hepatitis G virus (HGV), in Myanmar. The study population of 403 subjects consisted of 213 healthy individuals residing in the city of Yangon, Myanmar, and the surrounding suburbs and 190 ...

BACKGROUND The risk of anti-tuberculosis (TB) drug-induced liver injury (DILI) in patients with chronic viral hepatitis (CVH) is not clear. The aim of this study was to investigate incidence and risk factors associated with TB DILI in CVH and non-CVH patients. METHODS Retrospectively, a total of 128 CVH patients who received anti-TB medication from January 2005 to February 2014 were reviewed....

BACKGROUND Previous reports in Taiwan have shown that the hepatitis B virus (HBV)- and hepatitis C virus (HCV)-endemic areas are also endemic for hepatitis D virus (HDV), GBV-C and TT virus. This study aimed to elucidate the epidemiology of HDV and GBV-C infection in two neighboring HBV- and HCV-endemic villages, to deduce the epidemiological characteristics of multiple viral infections in comm...

INTRODUCTION Illicit drug users (DUs) are vulnerable to hepatitis C virus (HCV) infection. The shared use of illicit drugs is the main method of HCV transmission. METHODS A cross-sectional study was conducted in Breves, in northern Brazil. We surveyed 187 DUs to determine the prevalence of and factors associated with HCV infection. RESULTS The prevalence of anti-HCV antibodies was 36.9%, an...

Hepatitis C virus (HCV) is a leading cause of chronic viral hepatitis worldwide. The study of antibody-mediated virus neutralization has been hampered by the lack of an efficient and high-throughput cell culture system for the study of virus neutralization. The HCV structural proteins have been shown to assemble into noninfectious HCV-like particles (HCV-LPs). Similar to serum-derived virions, ...

We tested the frequency of occult hepatitis B infection (OBI) among Egyptian healthcare workers (HCWs). We tested 132 HCWs for hepatitis B virus (HBV) DNA by nested polymerase chain reaction (PCR), and hepatitis C virus antibody (anti-HCV) by ELISA. HCV RNA was measured by nested PCR in anti-HCV-positive HCWs. HBV-DNA-positive HCWs were subjected to HBV genotyping. We included 132 HCWs who were...

To investigate the markers useful for evaluating the long-term efficacy of interferon (IFN) therapy, the quantity of hepatitis C virus (HCV) RNA and two anti-HCV antibody titers (anti-N14 and anti-C-100-3 antibody) in 21 chronic hepatitis C patients were determined. In all complete responders, a sustained clearance of the virus and reductions in the anti-HCV antibody titers were observed during...

hepatitis c virus (hcv) infection is a serious public health concern throughout the world. despite its public health prominence, however, how surveillance systems for hepatitis c should be designed is still a challenging issue especially in developing countries such as iran. establishing a surveillance system needs an ongoing process of case investigation, data collection, analysis of data and ...