نتایج جستجو برای: hepatocellular carcinoma cell line

تعداد نتایج: 2165752  

Journal: :Journal of hepatology 2014
Sha Sha Zeng Taro Yamashita Mitsumasa Kondo Kouki Nio Takehiro Hayashi Yasumasa Hara Yoshimoto Nomura Mariko Yoshida Tomoyuki Hayashi Naoki Oishi Hiroko Ikeda Masao Honda Shuichi Kaneko

BACKGROUND & AIMS Recent evidence suggests that hepatocellular carcinoma can be classified into certain molecular subtypes with distinct prognoses based on the stem/maturational status of the tumor. We investigated the transcription program deregulated in hepatocellular carcinomas with stem cell features. METHODS Gene and protein expression profiles were obtained from 238 (analyzed by microar...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2005
Terence K Lee Kwan Man Joanna W Ho Xiang Hong Wang Ronnie T P Poon Yang Xu Kevin T Ng Alan C Chu Chris K Sun Irene O Ng Hui Chuan Sun Zao You Tang Ray Xu Sheung Tat Fan

PURPOSE Recurrence after resection and metastasis are common in hepatocellular carcinoma and are associated with poor prognosis. Therefore, effective treatment is urgently needed for improvement of patients' survival. Previously, we reported that FTY720 has an antimetastatic effect on hepatocellular carcinoma cell line through down-regulation of Rac signaling pathway. This study aims to investi...

Journal: :hepatitis monthly 0
shahrzad yazdanpanah department of pathology, shiraz university of medical sciences, shiraz, ir iran bita geramizadeh department of pathology, shiraz university of medical sciences, shiraz, ir iran; transplant research center, shiraz university of medical sciences, shiraz, ir iran; department of pathology, transplant research center, shiraz university of medical sciences, shiraz, ir iran. tel/fax: +98-7136473238 saman nikeghbalian transplant research center, shiraz university of medical sciences, shiraz, ir iran; department of surgery, hepatobiliary and liver transplant section, shiraz university of medical sciences, shiraz, ir iran seyed ali malek-hosseini transplant research center, shiraz university of medical sciences, shiraz, ir iran; department of surgery, hepatobiliary and liver transplant section, shiraz university of medical sciences, shiraz, ir iran

conclusions scc, lgdn, and hgdn are common associated findings and precursors of hcc in livers infected with hepatitis b. a strict follow-up and a precise and thorough sampling of livers with scc and any abnormal dysplastic nodules (dns), especially those larger than 1 cm, are highly recommended because these dns are highly associated with malignancy. results among all explanted cirrhotic liver...

Journal: :Cellular & molecular immunology 2006
Yongyan Chen Min Cheng Zhigang Tian

Chronic HBV infection is associated with a 100-fold high risk of developing hepatocellular carcinoma. Tumor recognition is of the most importance during the immune surveillance process that prevents cancer development in humans. In the present study, the expressions of MHC class I molecules on hepatoplastoma cell line HepG2.2.15 were investigated to indicate the possible effects of HBV on the i...

Two set of 2-aryl-5,6-dihydropyrrolo[2,1-a] isoquinolines were designed and synthesized to evaluate their biological activities as topoisomerase inhibitors. Cytotoxic activity of the synthesized compounds 4a-e and 7a-d was assessed against several human cancer cell lines, including MCF-7 (breast cancer cell), HepG2 (liver hepatocellular cells), A549 (adenocarcinomic human alveolar basal epithel...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2010
Qing Chen Wenjia Lou Junjie Shen Leina Ma Zhi Yang Li Liu Jingjing Luo Cheng Qian

PURPOSE Recent studies have indicated that short hairpin RNA (shRNA) driven by RNA polymerase (Pol) II promoters can be transcribed into precursor mRNAs together with transgenes. It remains unclear, however, whether coexpression of shRNA and transgene from a single promoter is feasible for cancer therapy. EXPERIMENTAL DESIGN In this study, we generated novel adenoviral vectors that permitted ...

Journal: :gastroenterology and hepatology from bed to bench 0
irappa madabhavi department of medical and pediatric oncology, gcri, ahmedabad, gujarat, india apurva patel department of medical and pediatric oncology, gcri, ahmedabad, gujarat, india mukesh choudhary department of medical and pediatric oncology, gcri, ahmedabad, gujarat, india asha anand department of medical and pediatric oncology, gcri, ahmedabad, gujarat, india harsha panchal department of medical and pediatric oncology, gcri, ahmedabad, gujarat, india sonia parikh department of medical and pediatric oncology, gcri, ahmedabad, gujarat, india

hepatocellular carcinoma (hcc) is the most common, malignant tumor of the liver. hepatocellular carcinoma (hcc) commonly metastasizes to the lungs, abdominal lymph nodes, adrenal glands, or bones. distant lymph node metastases are rare in hepatocellular carcinoma. a 49-year-old male patient presented with right sided neck mass. on examination there was right cervical lymphadenopathy and hepatom...

A. Ezzi M.H. Hablolvarid M.R. Gholami

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