Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for liver injury.The present study was conducted to evaluate the hepatoprotective activity of aqueous ethanolic extract of aerial parts of Basella rubra in wistar rats. The studies were conducted using the two popular inducing agents Paracetamol (2gm/kg,p.o.) in 1% CMC and Carbon tetrachloride (...

One of the most common causes of chronic liver disease, nonalcoholic fatty liver disease (NAFLD), is strongly associated with obesity and dysregulated insulin action in the liver. However, there are no pharmacological agents currently established for the treatment of NAFLD. A flowering plant in the Asteraceae family, Cirsium japonicum (CJ), exhibits a variety of pharmacological and antioxidativ...

Acetaminophen (APAP) known as paracetamol is the main ingredient in Tylenol, which has analgesic and anti-pyretic properties. Inappropriate use of APAP causes major morbidity and mortality secondary to hepatic failure. Overdose of APAP depletes the hepatic glutathione (GSH) rapidly, and the metabolic intermediate leads to hepatocellular death. This article reviews the mechanisms of hepatotoxici...

Preparations of isolated liver cells, either freshly prepared or in culture, have been available for many years; however, because they lack the polarization of the cell in the tissue, their application to the study of processes involved in bile formation has been very limited. The hepatocyte couplet model offers a unique opportunity to study in vitro the intracellular processes involved: not on...

the ethanolic extract of ficus carica leaves was screened for hepatoprotective and antioxidant activity in hepatotoxic albino rats induced via carbon tetrachloride. the degree of protection was measured by estimating biochemical parameters such as serum glutamate oxaloacetate transaminase (sgot), serum glutamate pyruvate transaminase (sgpt), total protein (tp), total albumin (ta), alkaline phos...

The ethanolic extract of Ficus carica leaves was screened for hepatoprotective and antioxidant activity in hepatotoxic Albino rats induced via carbon tetrachloride. The degree of protection was measured by estimating biochemical parameters such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), total protein (TP), total albumin (TA), alkaline phos...

The ethanolic extract of Ficus carica leaves was screened for hepatoprotective and antioxidant activity in hepatotoxic Albino rats induced via carbon tetrachloride. The degree of protection was measured by estimating biochemical parameters such as serum glutamate oxaloacetate transaminase (SGOT), serum glutamate pyruvate transaminase (SGPT), total protein (TP), total albumin (TA), alkaline phos...