Methionine is an indispensable amino acid that, when not incorporated into protein, is converted into the methyl donor S-adenosylmethionine as entry into the methionine cycle. Following transmethylation, homocysteine is either remethylated to reform methionine or irreversibly trans-sulfurated to form cysteine. Methionine flux to transmethylation and to protein synthesis are both high in the neo...

Methionine (Met) is an essential amino acid that is needed for the synthesis of S-adenosylmethionine (AdoMet), the major biological methylating agent. Methionine used for AdoMet synthesis can be replenished via remethylation of homocysteine. Alternatively, homocysteine can be converted to cysteine via the transsulfuration pathway. Aberrations in methionine metabolism are associated with a numbe...

Herbal medicine is used as the primary source of healthcare for approximately 75-80% of the world population and its use is particularly widespread in the developing countries, where it is considered more culturally acceptable, less dangerous and a more natural form of medicine that is compatible with the human body. Herbal products are defined as “herbal preparations produced by subjecting her...

BACKGROUND The use of herbal medicines among pregnant women in Nigeria has not been widely studied. METHODS Opinion of 595 pregnant women in three geopolitical zones in Nigeria on the use of herbal medicines, safety on usage, knowledge of potential effects of herbal remedies on the fetus and potential benefits or harms that may be derived from combining herbal remedies with conventional thera...

The Panel noted that N-acetyl-L-methionine is deacetylated in animals and humans to Lmethionine. The bioavailability of methionine from N-acetyl-L-methionine is comparable to that from L-methionine used as such as similar mean plasma methionine concentrations were recorded in pigs and in humans after loading with equimolar quantities of each, as L-methionine and Nacetyl-L-methionine were equall...

The nitrogen-sparing effect of methionine, methionine sulphoxide, homocystine, cystine and choline was studied in rats by determining dialy N excretions during 5 d after changing from a high-protein diet to a protein-free diet, L-glutamic acid was used as a negative control. 2. L-, D- and DL-methionine were equally active in sparing N. L-methionine sulphoxide, DL-homocystine and L-cystine were ...

Introduction Women often use herbal remedies as a complement or alternative to traditional medicine. Guided by the Comprehensive Model of Information Seeking, this study examined use of herbal remedies among mothers of young children living in the Central Appalachian Region. Methods A cross-sectional study was conducted among mothers of young children (n = 178). The outcome measure of interes...

The superiority of d-methionine over l-methionine for stimulation of cephalosporin C synthesis in a crude medium was confirmed. The optimal level of dl-methionine was 0.5%. Methionine stimulates growth slightly but this is not thought to be the cause of the marked stimulation of antibiotic synthesis. Of a large number of sulfur compounds tested, only dl-methionine-dl-sulfoxide and S-methyl-l-cy...

1. L-[U-14C]methionine was used to study methionine metabolism in sheep fed on untreated silage, silage treated with formaldehyde and untreated silage plus intraperitoneal infusion of L-methionine. 2. Over-all the values ranged from 0.43 to 0.86 mmol/h for methionine turnover rate, from 13.3 to 19.9 for the percentage of methionine oxidized to carbon dioxide and from 245 to 1089 mumol for methi...

The conversion of methionine to cyst(e)ine was determined in sheep infused with different amounts of methionine (0-5 g/d) into the duodenum by assaying the incorporation of 35S from intravenously-infused L-[35S]methionine into cyst(e)ine in wool, plasma albumin and the free plasma pool. The percentage of cystine-S in the plasma originating from methionine increased linearly from 4.5 to 18 with ...