Interaction of staphylococcal protein A (SPA) with human serum depressed the ability of such serum to neutralize herpes simpled virus (HSV)-antibody labialis. SPA-induced depression of serum-dependent virus neutralization appeared to be due to consumption of complement by SPA. In addition, SPA attached to antibody-treated, HSV-infected cells and inhibited complement mediated immune cytolysis. T...

Honey is the nectar that is collected from many plants and processed by honey bees (Apis mellifera). This study is a pilot study that observes and evaluates the clinical efficacy of topical application of honey bees in treatment of some common inflammatory, vesiculobullous and ulcerative oral lesions. A total number of 50 patients complaining of different oral lesions were enrolled in this stud...

The objective of the study is to evaluate the efficacy and safety of oral inosine pranobex as compared with acyclovir in the treatment of recurrent herpes labialis (RHL) and recurrent herpes genitalis (RHG). A multicenter double-blind, double-dummy, randomized, controlled, parallel group trial was conducted in 144 patients with RHL and 144 RHG. Patients were assigned to treatment in one of two ...

more frequently in the spring and the fall, and a relationship to temperature or to changes in temperature may be involved (unpublished observations, Kaufman HE, 1981; Barren BA, 1994). The appearance of fever blisters and clinical herpes during temperature stress in hudans is a well-known clinical phenomenon. Our primate model may provide a way to study this relationship in a laboratory settin...

OBJECTIVE To study the epidemiologic aspects of recurrent herpes labialis (RHL) in a young adult population and to evaluate treatments used by affected patients. METHODS A cross-sectional survey conducted on a random sample of 1000 students of The University of Jordan, Amman, Jordan between May and September 2008. Subjects with RHL were identified and asked to describe their disease and its m...

Vol. 27, No. 1, 2015 97 Received October 22, 2013, Revised February 17, 2014, Accepted for publication February 19, 2014 Corresponding author: Nilendu Sarma, Department of Dermatology, Nilratan Sircar Medical College, 138 AJC Bose Road, Kolkata 700014, India. Tel: 91-9830382498, E-mail: [email protected] This is an Open Access article distributed under the terms of the Creative Commons A...

BACKGROUND The efficacy of many preparations for topical use in herpes infections have remained rather disappointing. The development of new antiviral drugs, especially herbal preparations, thus remains desirable. In a screening study with plant extracts, a rhubarb root extract and a sage extract showed a promising activity. OBJECTIVE The efficacy of a combined topical preparation with rhubar...