Histocompatibility (HLA) testing was performed on a total of 171 black Americans, 129 controls, and 42 patients with iridocyclitis. None of the patients had a history of rheumatological disease. The phenotype frequency of HLA B8 was greatly increased among patients than the control group (exact p = 0.0010). Most striking was the almost identical phenotypic frequency of B27 found in patients and...

Most patients with Reiter's syndrome (RS) or B27associated conditions respond well to non-steroidal anti-inflammatory agents. Hence there is no need for corticosteroid therapy or immune modulation in mild cases. Aggressive treatment should be considered only if a patient develops severe systemic manifestations such as vasculitis or iridocyclitis or the disease has a prolonged, crippling course ...

UCHS HETEROCHROMIC CYCLITIS (FHC) IS A CHRONIC, typically unilateral anterior segment uveitis syndrome.1 It is usually painless with limited inflammation characterized by diffuse, scattered, small and mediumsized keratic precipitates with mild anterior chamber flare, minimal anterior chamber cells, and iris atrophy that leads to secondary, acquired heterochromia. Immunohistochemistry of iris bi...

AIM The histopathological features of the iris in leprosy were studied by light microscopy. METHOD Formalin fixed and paraffin embedded iris tissue excised during cataract surgery from 20 leprosy patients were sectioned and studied with haematoxylin and eosin stain and modified Fite Faraco's stain for acid fast bacilli (AFB). RESULTS Chronic inflammatory reactions were seen in the iris of 1...