Limitations in our ability to predict cardiovascular risk have fueled efforts to identify novel risk markers and to refine the measurement of traditional risk factors, such as low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). Standard assays to evaluate LDL-C and HDL-C quantify the cholesterol content within the respective lipoprotein fraction. Howeve...

Freshly prepared rat testicular membranes bind iodinated rat high density lipoprotein (HDL) with high affinity (Kd = 32 microgram of HDL protein/ml). This high density lipoprotein binding differs from low density lipoprotein binding by cultured human fibroblast cells in two ways; it is not affected by Ca2+ or ethylenediaminetetraacetic acid, and it is not sensitive to pronase and trypsin. Testi...