نتایج جستجو برای: high throughput computing

تعداد نتایج: 2411664  

Journal: :Bioinformatics 2014
Tiffany J. Morris Lee M. Butcher Andrew Feber Andrew E. Teschendorff Ankur R. Chakravarthy Tomasz K. Wojdacz Stephan Beck

UNLABELLED The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylat...

2007
Jeff Linderoth François Margot Greg Thain

Symmetry Reduction and High-Throughput Computing Jeff Linderoth Department of Industrial and Systems Engineering, The University of Wisconsin-Madison, 3226 Mechanical Engineering Building, 1513 University Ave., Madison, WI 53706, USA, [email protected] François Margot Tepper School of Business, Carnegie Mellon University, 5000 Forbes Ave., Pittsburgh, PA 15213-3890, USA, [email protected]...

2008
Nuno Bandeira Julio Ng Dario Meluzzi Roger G. Linington Pieter C. Dorrestein Pavel A. Pevzner

While nonribosomal peptides (NRPs) are of tremendous pharmacological importance, there is currently no technology capable of highthroughput sequencing of NRPs. Difficulties in sequencing NRPs slow down the progress in elucidating the non-ribosomal genetic code and negatively affect various screening programs aimed at the discovery of natural compounds of medical importance. We propose to employ...

2006
Bobbie-Jo M. Webb-Robertson William R. Cannon Joshua N. Adkins Deborah K. Gracio

High-throughput proteomics is a rapidly developing field that offers the global profiling of proteins from a biological system. These high-throughput technological advances are fueling a revolution in biology, enabling analyses at the scale of entire systems (e.g., whole cells, tumors, or environmental communities). However, simply identifying the proteins in a cell is insufficient for understa...

2009
P. Alexander Rolfe

A Ruler Array measures the distance between a set of microarray probes and a set of experimentally defined locations in a nucleic acid, offering new possibilities for locating and characterizing changes in the nucleic acid sequence. Despite the known relevance of genomic changes to pathogens, cancer, development, and evolution, many of these changes evade detection by existing high-throughput t...

2017
Max Ruas Valentin Guignon Guilhem Sempere Julie Sardos Yann Hueber H. Duvergey Alain Andrieu Richard Chase C. Jenny Tom Hazekamp Brian M. Irish K. Jelali J. Adeka Tomás Ayala-Silva C. P. Chao Jeff W. Daniells B. Dowiya B. Effa effa L. Gueco L. Herradura L. Ibobondji E. Kempenaers J. Kilangi S. Muhangi P. Ngo Xuan J. Paofa Claudie Pavis Deless Thiémélé Colette Tossou Jeffrey Sandoval Asti Sutanto G. Vangu Paka Guilian Yi Ines van den houwe Nicolas Roux Mathieu Rouard

Database URL https://www.crop-diversity.org/mgis/.

2002
Harald Steck Tommi S. Jaakkola

Motivation & Previous Work: A common objective in learning a model from data is to recover its network structure, while the model parameters are of minor interest. For example, we may wish to recover regulatory networks from high-throughput data sources. Regularization is essential when learning from finite data sets. It provides not only smoother estimates of the model parameters compared to m...

Journal: :Concurrency and Computation: Practice and Experience 2015
Anubhav Jain Shyue Ping Ong Wei Chen Bharat Medasani Xiaohui Qu Michael Kocher Miriam Brafman Guido Petretto Gian-Marco Rignanese Geoffroy Hautier Dan Gunter Kristin A. Persson

Environmental Energy and Technologies Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA Department of Nanoengineering, University of California San Diego, La Jolla, CA 92093, USA Computational Research Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA Institute of Condensed Matter and Nanosciences (IMCN), European Theoretical Spectroscopy Facility (...

Journal: :CoRR 2017
Ailidani Ailijiang Aleksey Charapko Murat Demirbas Tevfik Kosar

We present WPaxos, a multileader wide area network (WAN) Paxos protocol, that achieves low-latency high-throughput consensus across WAN deployments. WPaxos dynamically partitions the global object-space across multiple concurrent leaders that are deployed strategically using flexible quorums. This partitioning and emphasis on local operations allow our protocol to significantly outperform leade...

2008
Lucas Lochovsky Thodoros Topaloglou

An important prerequisite to successfully integrating protein data is detecting duplicate records spread across different databases. In this paper, we describe a new framework for protein entity resolution, called PERF, which deduplicates protein mentions using a wide range of protein attributes. A mention refers to any recorded information about a protein, whether it is derived from a database...

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