The cytoplasmic polyadenylation element binding protein (CPEB) homologue Orb2 is a functional amyloid that plays a key regulatory role for long-term memory in Drosophila. Orb2 has a glutamine, histidine-rich (Q/H-rich) domain that resembles the Q/H-rich, metal binding domain of the Hpn-like protein (Hpnl) found in Helicobacter pylori. In the present study, we used chromatography and isothermal ...

Background: Plasmodium falciparum histidine rich protein 2/3 gene deletions (Pfhrp2/3gd) threatens usefulness of mRDT in diagnosing malaria cases. This review was performed to assess the methods used report findings on those between January 2010 and December 2021.
 Methods: Present search using Medline, Google Scholar PubMed.
 Results: Out 94 articles identified, 19% (n=18) were inclu...

The proximate composition of pen shell adductor muscle (PSAM) was determined, and its nutrition value was evaluated. Proximate composition analysis indicated that PSAM contained 91.07% (w/w) protein, 5.77% (w/w) ash, and 2.46% (w/w) fat. Calcium was the predominant mineral followed by zinc and then iron. The amino acid profile was in accordance with the recommended pattern of FAO/WHO except for...

In studies on the nature of the enzymic defect in patients with histidinaemia, an inborn error of histidine metabolism (La Du, Howell, Jacoby, Seegmiller & Zannoni, 1962), it was necessary to develop a sensitive assay procedure to measure histidine oc-deaminase (L-histidine ammonia-lyase, EC 4.3.1.3), the enzyme that converts histidine into urocanic acid. The application of this method has show...

Redox active transition metal ions (e.g., iron and copper) have been implicated in the etiology of many oxidative stress-related diseases including also neurodegenerative disorders. Unbound copper can catalyze formation of reactive oxygen species (hydroxyl radicals) via Fenton reaction/Haber-Weiss chemistry and therefore, under physiological conditions, free copper is potentially toxic and very...