Methods: Critical-sized defects were created in rat calvariae and GBR procedures were performed with a collagen membrane either alone (control), plus bolus delivery of VEGF, or plus application of VEGF releasing hydrogels (VEGF Alg). Four and eight weeks following treatment, defect sites were evaluated with microcomputed tomographic and histomorphometric analyses for blood vessel and bone forma...

Background: Saffron consists of dried stigmas and top of the styles of crocus sativus. It has various applications such as sexual potential stimulant, anti spasm, anti depression, sedative ,anti inflammation and anti cancer. Materials and Methods: In present study, 200 male adult rats divided to five groups with 10 rats per each cage and with four replicate for each group. Solvent of saffron wa...

different wettability using resonance frequency analysis (RFA) and histomorphometric analysis (bone implant contact, BIC; and bone area fraction occupied, BAFO) after 2 and 4 weeks in rabbit tibiae. Thirty-two Morse taper implants (length 7 mm, diameter 3.5 mm) were divided according to surface characteristics (n=8): Neo, sandblasted and dual acidetched; and Aq, sandblasted followed by dual aci...

BACKGROUND Various clinical reports suggest etanercept (ETN) has some efficacy in bone formation in rheumatoid arthritis (RA). To examine this effect, we investigated the gene expression of cytokines relevant to osteoblast/osteoclast differentiation, and evaluated histomorphometric findings in mature rats with collagen-induced arthritis (CIA). METHODS Total RNA was extracted from knee joints ...

PURPOSE The purpose of this study was to assess the effect of systemically administered oxytocin (OT) on the implant-bone interface by using histomorphometric analysis and the removal torque test. MATERIALS AND METHODS A total of 10 adult, New Zealand white, female rabbits were used in this experiment. We placed 2 implants (CSM; CSM Implant, Daegu, South Korea) in each distal femoral metaphys...

OBJECTIVE The aim of this study was to compare the lateral window and osteotome techniques for sinus lifting using histological and histomorphometric methods. MATERIALS AND METHODS In this clinical trial 10 patients (a total number of 14 sinus areas) who needed implant treatment in the atrophic posterior maxilla were enrolled. In all the cases the residual bone height between the sinus floor ...

brachiocephalic arteries in quails are large arteries which are arising separately from the aortic arch. the aim of the present study was to determine the histomorphometric aspects of brachiocephalic arteries in the japanese quail. the different layers of the brachiocephalic artery were studied quantitatively in 10, 20 and 60 days-old japanese quail; (n = 6) and both sexes. luminal diameter, th...

we aimed to evaluate the potential of growing rats as a model of osteoporosis induced by short term hypercholesterolemia. twelve growing female sprague-dawley rats were randomly allocated into two groups. control rats received standard diet while rats in group 2 were fed with diet contained 20% sunflower oil, 2% cholesterol and 0.5% cholic acid for 2 weeks and then a diet contained 10% sunflowe...

PURPOSE The purpose of this animal study was to perform a histological and histomorphometric analysis in order to elucidate the effect of fibroblast growth factor-2 (FGF-2) on injured periodontal ligament (PDL) and cementum after tooth replantation in dogs. METHODS The roots of 36 mandibular premolars from six mongrel dogs were used in this study. The roots were randomly divided into three gr...

Statement of Problem: Reconstruction methods are an essential prerequisite for functional rehabilitation of the stomatognathic system. Platelet-rich plasma (PRP) offers a new and potentially useful adjunct to bone substitute materials (e.g. Xenografts) in oral and maxillofacial bone and implant reconstructive surgery. Purpose: An animal study was carried out to investigate the influence of PRP ...