INTRODUCTION Prolonged steroid treatment administered to any patient can cause visceral obesity, which is associated with metabolic disease and Cushing's syndrome. Glucocorticoids have a profound negative effect on adipose tissue mass, giving rise to obesity, which in turn is regulated by the 11β-hydroxysteroid dehydrogenase type 1 enzyme. Adrenalectomized rats treated with dexamethasone exhibi...

Received 13 April 2013 Revised 10 July 2013 Accepted 12 July 2013 Early online 25 July 2013 Print 31 August 2013 Monosodium Glutamate (MSG) is widely used as a flavor enhancer throughout the world. MSG contains glutamic acid, sodium and water. Glutamic acid serves as a neurotransmitter vital to the transmission of nerve impulses in many parts of the central nervous system, and in excess it may ...

AIM To compare the effectiveness of two-ridge preservation treatments. MATERIALS AND METHODS Forty subjects with extraction sockets exhibiting substantial buccal dehiscences were enrolled and randomized across 10 standardized centres. Treatments were demineralized allograft plus reconstituted and cross-linked collagen membrane (DFDBA + RECXC) or deproteinized bovine bone mineral with collagen...

INTRODUCTION Contrast-induced nephropathy (CIN) is a major iatrogenic cause of acute kidney injury. Experimental studies have shown that intravascular injection causes intense vacuolization of the contrast agent in the proximal renal tubules cells, preceding the increase in serum creatinine, and that the female may be at a higher risk for CIN. OBJECTIVE To study the early kidney histomorphome...

INTRODUCTION All good tissue specimen preparations require complete fixation. The process of tissue handling and processing from patient to paraffin block is too frequently invisible to the pathologists. Many times due to certain emergencies or unavailability of a proper fixative, tissues are kept in different carrying media such as normal saline (NS) or local anesthetic till the availability o...

Nadroparin calcium is a low-molecular-weight heparin. Low-molecular-weight heparins have a number of advantages over standard heparin (heparin), but it is not clear if low-molecular-weight heparins have less effect on bones than heparin. Administration of heparin can lead to osteoporosis. The aim of the present study was to investigate the effects of nadroparin on the rat osseous system and com...

ObjectiveTo evaluate a rabbit model of mandibular box-shaped defects created through an intraoral approach and determine the minimum size defect that would not spontaneously heal during rabbit's natural life (or critical-sized defect, CSD).MethodsForty-five 6-month-old rabbits were randomly divided into five groups (nine each). Mandibular different sizes (4, 5, 6, 8, 10 mm) in each hemimandible...