Purpose. To report the visual, refractive, and corneal topography and wavefront aberration results of accelerated corneal cross-linking (CXL) during a 24-month follow-up. Methods. Forty-seven eyes underwent riboflavin-ultraviolet A-induced accelerated CXL treatment (30 mW/cm2 with a total dose of 7.2 joules/cm2). Uncorrected distance visual acuity (UDVA), corrected distance visual acuity (CDVA)...

Refractive error, higher order aberrations (HOA), axial length (AL), anterior chamber depth (ACD) and average corneal radius of curvature were measured after cycloplegia from 166 emmetropic participants at the Sydney Myopia Study (SMS, 2004-2005, age 12.63 ± 0.48 years). Measurements were repeated approximately 5 years later at the Sydney Adolescent Vascular and Eye Study (SAVES, 2009-2010, age...

In contrast to two other multichannel sound-field synthesis techniques, Higher Order Ambisonics (HOA) and Wavefield Synthesis (WFS), Discrete Multichannel Simulation (DMS) has distinct advantages in the display of three-dimensional virtual acoustic sound fields for human listeners. In particular, it is the impact of listener head movements on reproduction fidelity that is the primary concern, a...

BACKGROUND To identify baseline radiographic features that predict hip osteoarthritis (HOA) progression, and to explore differences in these associations by race. METHODS Radiographs from the community-based Johnston County OA Project were scored using Kellgren-Lawrence (KL) grade and for presence and location of joint space narrowing (JSN), osteophytes, and subchondral changes. Associations ...

OBJECTIVE The novel synergistic drug candidate CRx-102 comprises dipyridamole and low dose prednisolone and is in clinical development for the treatment of immunoinflammatory diseases. The purpose of this clinical study was to examine the efficacy and safety of CRx-102 in patients with hand osteoarthritis (HOA). METHODS The study was conducted as a blinded, randomised, placebo-controlled tria...

Delamination is a type of representative damage in composite structures, severely degrading structural integrity and reliability. The identification of delamination is commonly treated as an issue of nondestructive testing. Differing from existing studies, a hybrid optimization algorithm HOA , combining particle swarm optimization PSO with simplex method SM , is proposed to identify delaminatio...

The novel high performance adaptive fidelity algorithms for automated multi-modality images’ feature detection, registration, and fusion is presented. The new fusion method, which consists of the Adaptive Fidelity Exploratory Algorithm (AFEA) and the Heuristic Optimization Algorithm (HOA), implements automatic adaptation from frame to frame with a few tunable thresholds. The new algorithms have...

Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic...

PURPOSE To investigate normal anterior segment parameters and analyze the possible influencing factors using a dual Scheimpflug system. SETTING Department of Ophthalmology, Affiliated Sixth People's Hospital Shanghai Jiao Tong University, Shanghai, China. DESIGN A prospective observational case series. METHODS A total of 153 normal subjects (153 eyes) were studied. The anterior segment pa...

Three white male patients with advanced cavitary pulmonary tuberculosis presented with HOA. No other pathology to explain the osteoarthropathy was detected. The osteoarthropathy responded symptomatically to NSAI drugs and treatment of tuberculosis but resolved radiologically in only one patient.