objective: the autoimmune diseases tend to coexist with diabetes mellitus type i (t1dm). the concomitance of these two types of diseases will lead to poor glycemic control beside their own complications. in this study the prevalence of thyroid disorder and celiac disease among t1dm patients in yazd, iran was evaluated. materials and methods: all the patients diagnosed as t1dm in yazd younger th...

background world health organization/international society of hypertension (who/ish) charts have been employed to predict the risk of cardiovascular outcome in heterogeneous settings. the aim of this research is to assess the prevalence of cardiovascular disease (cvd) risk factors and to estimate the cardiovascular risk among adults aged >40 years, utilizing the risk charts alone, and by the ad...

in this study, immunohistochemistry was used to clarify the early stages of viral kinetics and cycliccourse of ibdv, ir499, which has been described earlier as a very virulent strain (vvibdv). fifteen, 4-week-old spf chickens were inoculated with 10³ eid50 of vvibdv, ir499, via oculo/nasal route. five birdsserved as controls, and inoculated with phosphate buffered saline (pbs). the birds were t...

normal 0 false false false en-us x-none fa background : fahr's disease is a rare neurodegenerative disorder of unknown cause characterized by idiopathic basal ganglia calcification that is associated with neuropsychiatric and cognitive impairment. no case of fahr's disease with associated cardiac conduction disease has been described in the literature to date. the objective of this case report ...

gene identification represents the first step to a better understanding of the physiological role of the underlying protein and disease pathways, which in turn serves as a starting point for developing therapeutic interventions. familial hypercholesterolemia is a hereditary metabolic disorder characterized by high low-density lipoprotein cholesterol levels. hypercholesterolemia is a quantitativ...

background: gastrointestinal and liver diseases (gilds) are major causes of death and disability in middle east and north africa (mena). however, they have different patterns in countries with various geographical, cultural, and socio-economic status. we aimed to compare the burden of gilds in iran with its neighboring countries using the results of the global burden of disease (gbd) study in 2...

crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...

background: the prevalence of vitamin d deficiency is higher in end-stage renal disease (esrd) patients compared to healthy populations. this deficiency could lead to several complications with different mechanisms and might result in reduced survival in patients. leptin and adiponectin are messenger proteins with endocrine secretion from adipocytes and various effects in cellular mechanisms. t...

conclusion most cte findings correlated with cdai and crp in patients with active crohn’s disease. background the accurate evaluation of crohn’s disease activity is important for the treatment of the disease and for monitoring the response. computerized tomography (ct) enterography is a useful imaging modality that reflects enteric inflammation, as well as extramural complications. objectives t...

background: the seladin-1 (selective alzheimer disease indicator-1), also known as dhcr24, is a gene found to be down-regulated in brain region affected by alzheimer disease (ad). whereas, hair follicle stem cells (hfsc), which are affected in with neurogenic potential, it might to hypothesize that this multipotent cell compartment is the predominant source of seladin-1. our aim was to evaluate...