AIMS The region-specific mechanical function of left ventricular (LV) murine cardiomyocytes and the role of phosphorylation and oxidative modifications of myofilament proteins were investigated in the process of post-myocardial infarction (MI) remodelling 10 weeks after ligation of the left anterior descending (LAD) coronary artery. METHODS AND RESULTS Permeabilized murine cardiomyocytes from...

Methanol carbonylation on Rh and Ir organometallic complexes with iodide co-catalysts is currently used to produce acetic acid. Catalyst cost and recovery, as well as the toxic and corrosive nature of iodide compounds, has led a search for alternate routes, such as zeolite acid catalysts for methanol or dimethyl ether carbonylation and dispersed metal oxide domains for the oxidation of ethane, ...

Absolute attachment cross sections of single molecules M (M = water, ethanol, or methanol) onto positively charged mass-selected clusters XnH(+) (X = water, ethanol, or methanol) were measured for cluster sizes ranging from tens to hundreds of molecules and center-of-mass collision energies varying from 0.1 to ∼1 eV. The attachment cross sections, which converge as expected toward geometrical c...

We present the results of a statistical survey of the 6.7 GHz CH3OH and 22.2 GHz H2O emissions towards a large homogeneous sample of ultracompact (UC) H ii regions, performed to investigate the nature of the methanol emission: does it point out ionized regions or does it trace earlier stages of the star forming process? The present detection rates are almost identical: 23% for CH3OH and 22% for...

Free-standing, ZnO surface decorated Cu nanoparticles of 1-3 nm size were obtained by sequential co-pyrolysis of [Cu(OCHMeCH2NMe2)2] and ZnEt2 in squalane in the absence of additional surfactants and proved to be highly active quasi homogeneous catalysts for methanol synthesis from CO and H2.

amodiaquine is an antimalarial drug used in the prophylaxis and treatment of this disease. however, hepatotoxicity as a life‑threatening adverse effect is associated with its clinical use. we evaluated amodiaquine-induced toxicity in isolated rat hepatocytes as an in vitro model for studying drug‑induced hepatotoxicity. this study attempts to investigate the protective effects of taurine and n-...

Exposure to arsenic is linked a wide range of diseases, in particular male reproductive toxicities. Trametes versicolor traditional medicinal fungus with remarkable potential for antioxidant activity. The purpose this study was examine the ameliorating effects water and methanol extracts T. on arsenic-induced toxicities via abrogation oxidative stress. mice were divided as follows: control: nor...

Due to the high price of virgin vegetable oils and the drawbacks of the homogeneous catalytic transesterification, in this work an economically profitable alternative process was proposed for biodiesel synthesis in which transesterification of the low-cost waste cooking oil (WCO) with methanol in a heterogeneous system was done. Alumina impregnated with sodium hydroxide was utilized as a solid ...

A tandem transformation of C-N coupling/C-H carbonylation has been developed for the synthesis of benzo-1,4-oxazepine pharmaceutically derivatives. Notably, this reaction was accomplished by various phenylamine with ally halides under carbon dioxide atmosphere employing 2-(2-dimethylamino-vinyl)-1H-inden-1-olcatalyzed. Furthermore, under the optimized conditions, various benzo-1,4-oxazepine der...