The present study establishes the analgesic and anti-pyretic activities of the ethanolic extract of leaves of Catharanthus roseus in the models used. Since antipyretic and analgesic activities are commonly mentioned as characteristic of drugs or compounds which have an inhibitory effect on prostaglandin biosynthesis, the yeast induced hyperthermia in rat model was, therefore, employed to invest...

How to improve the bonding ability and quality performance of heterogeneous plates has always been one difficult problems in field high-performance composite sheet forming manufacturing. In this paper, a new manufacturing method clad plate, hard plate rolling is proposed. The hot process Al/Mg/Al slab with or without was studied. results show that shear stress direction (RD) can be transformed ...

Tubercle bacilli, which survived heat fixation, were detected with a slide culture technique which allowed the entire smear to be examined. Both conventional flame fixation and the use of a controlled hot-plate failed to render tuberculous sputum smears safe for further handling. Smears which were stained with the phenol-auramine method failed to yield growth on culture. If delay between prepa...

The ethanolic extract of PC and SS were screened for its analgesicactivity using both tail flick and hot plate method. The extracts in a dose of 200mg/kh significantly increased the basal reaction time which is comparable to that of standard drug pentazocine 5mg/kg . From the results it is concluded that the alcoholic extract of the plants PC and SS exhibits analgesic activity by central mechan...

Slivers on the surface of rolled plates, which are serious defects for interstitial-free (IF) steel, occur mainly as a result inclusions in continuous casting (CC) slabs. It is, therefore, important to study CC slabs terms their migration towards during hot rolling. To investigate inclusion rolling ultralow carbon 3D numerical model was constructed using finite element method. The positions lay...

This study investigated the possible anti-inflammatory, analgesic, and antipyretic effects of ethanolic extract of Pedalium murex Linn. fruits in selected experimental animal models. Anti-inflammatory activity of Pedalium murex Linn., with doses of 200 mg/kg and 400 mg/kg, p.o., was evaluated by Lambda-carrageenan induced paw oedema in Wistar albino rats; analgesic activity with doses of 280 mg...

objective: vanillosmopsis arborea baker (asteraceae) has high economic value from chapada to araripe and its bark essential oil is a potential source of alpha-bisabolol. the present study aimed to elucidate the antinociceptive and antipruritic properties of the essential oil of v. arborea baker (eova) in mice. materials and methods: the antinociceptive activity was assessed using the capsaicin,...

Background & Aims: Iron is an essential element for correct brain function. Iron deficiency changes some behaviors such as anxiety and nociception. Recently, nano-iron, Ferric or ferro oxide (nano-Fe2O3 or Fe3O4), are used in various applications in agriculture, industry and medicine, but their effects on the heath and behavior is not clear. In this study, the effects of Fe2O3 nanoparticles on ...

Introduction: Pain research using animal models is related to ethical concerns, so invertebrates and insects have been recommended by researchers. In the present study, the nociceptive and antinociceptive effects of capsaicin, aspirin, morphine and chili extract were examined using fruit fly (Drosophila melanogaster) as an alternative for rodent pain model. Methods: Stage 3 of larvae and ad...