نتایج جستجو برای: hoxa11

تعداد نتایج: 175  

Journal: :Journal of the American Society of Nephrology : JASN 2013
Caroline E Hendry Jessica M Vanslambrouck Jessica Ineson Norseha Suhaimi Minoru Takasato Fiona Rae Melissa H Little

Direct reprogramming involves the enforced re-expression of key transcription factors to redefine a cellular state. The nephron progenitor population of the embryonic kidney gives rise to all cells within the nephron other than the collecting duct through a mesenchyme-to-epithelial transition, but this population is exhausted around the time of birth. Here, we sought to identify the conditions ...

Journal: :Development 2008
Philipp Leucht Jae-Beom Kim Raimy Amasha Aaron W James Sabine Girod Jill A Helms

The fetal skeleton arises from neural crest and from mesoderm. Here, we provide evidence that each lineage contributes a unique stem cell population to the regeneration of injured adult bones. Using Wnt1Cre::Z/EG mice we found that the neural crest-derived mandible heals with neural crest-derived skeletal stem cells, whereas the mesoderm-derived tibia heals with mesoderm-derived stem cells. We ...

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