نتایج جستجو برای: hspx

تعداد نتایج: 112  

2017
Eric Warren Garrett Teskey Vishwanath Venketaraman

Neutrophils have a significant yet controversial role in the innate immune response to Mycobacterium tuberculosis (M. tb) infection, which is not yet fully understood. In addition to neutrophils' well-known effector mechanisms, they may also help control infection of M. tb through the formation of neutrophil extracellular traps (NETs), which are thought to further promote the killing of M. tb b...

2016
Mia Urem Teunke van Rossum Giselda Bucca Geri F Moolenaar Emma Laing Magda A Świątek-Połatyńska Joost Willemse Elodie Tenconi Sébastien Rigali Nora Goosen Colin P Smith Gilles P van Wezel

Two-component regulatory systems allow bacteria to respond adequately to changes in their environment. In response to a given stimulus, a sensory kinase activates its cognate response regulator via reversible phosphorylation. The response regulator DevR activates a state of dormancy under hypoxia in Mycobacterium tuberculosis, allowing this pathogen to escape the host defense system. Here, we s...

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