Abstract Human cytomegalovirus (CMV) causes severe disease in immunocompromised individuals. CMV-based vectors are promising candidates vaccination and immunotherapy approaches. Here, we report on our approach to make chimpanzee CMV (CCMV) available for research vector development. We cloned the CCMV genome created a global picture of infection program by multi-omics. Via engineering distinct r...

Immunity mechanisms of cytomegalovirus infection control have been studied recently and have contributed to the better understanding of the pathogenesis of this disease in patients with a solid organ transplant. These studies suggest that a relationship exists between cytomegalovirus and the development of acute rejection. This relationship is more evident if the patient develops cytomegaloviru...