Part of the rationale for this practice is the high iron requirement during pregnancy, almost 3 times that required for nonpregnant women of childbearing years, which is difficult to meet from dietary sources. Another reason for supplementation is that anemia caused by iron deficiency alone or in combination with other factors, eg, folate deficiency, vitamin A deficiency, and malaria, has been ...

dicrocoelium dendriticum is 10 by 2 mm. trematodes which live in the liver of the cattle, goats and sheep but it occasionally infects the human being. during the study of intestinal infections in the caspian sea region 2 cases of dicrocoeliasis were found. the method for diagnosis was formol-ether concentration technique for stool examination. these two patients had eosinophilia and vague abdom...

Iron is an essential element for humans and physiological needs are determined by obligatory loss, growth, menstruation and pregnancy. Although iron metabolism occurs in a ‘closed circuit ’, physiological losses occur and they must be made good. Three factors are important in the study of iron needs: the total amount of iron in the diet; the nature of the iron compound; and other components of ...

development in the effort to control 1,2 micronutrient deficiencies . Iron deficiency anaemia (IDA) and iodine deficiency disorders (IDD) are the major micronutrient deficiencies of public 2,3 health importance in India . Salt is a universal vehicle for the fortification of iodine / iron as it is consumed at approximately the same levels throughout the year by all normal populations, with very ...

Ferritins and bacterioferritins are iron storage proteins that represent key players in iron homeostasis. Several organisms possess both forms of ferritins, however, their relative physiological roles are less understood. Mycobacterium tuberculosis possesses both ferritin (BfrB) and bacterioferritin (BfrA), playing an essential role in its pathogenesis as reported by us earlier. This study prov...

Iron requirements are greater in pregnancy than in the nonpregnant state. Although iron requirements are reduced in the first trimester because of the absence of menstruation, they rise steadily thereafter; the total requirement of a 55-kg woman is approximately 1000 mg. Translated into daily needs, the requirement is approximately 0.8 mg Fe in the first trimester, between 4 and 5 mg in the sec...

Heme is an iron-containing porphyrin ring that serves as a prosthetic group in proteins that function in diverse metabolic pathways. Heme is also a major source of bioavailable iron in the human diet. While the synthesis of heme has been well-characterized, the pathways for heme trafficking remain poorly understood. It is likely that heme transport across membranes is highly regulated, as free ...

THERE ARE TWO MAIN MECHANISMS BY WHICH IRON OVERLOAD DEVELOPS IN THALASSEMIAS: increased iron absorption due to ineffective erythropoiesis and blood transfusions. In nontransfused patients with severe thalassemia, abnormal dietary iron absorption increases body iron burden between 2 and 5 g per year. If regular transfusions are required, this doubles the rate of iron accumulation leading to ear...