نتایج جستجو برای: humanized
تعداد نتایج: 6443 فیلتر نتایج به سال:
BACKGROUND Recent studies with bone marrow (BM)-derived Mesenchymal Stromal Cells (MSC) in transplant recipients demonstrate that treatment with MSC is safe and clinically feasible. While BM is currently the preferred source of MSC, adipose tissue is emerging as an alternative. To develop efficient therapies, there is a need for preclinical efficacy studies in transplantation. We used a unique ...
Mice with human immune systems have evolved over the last three decades. Over the years, these humanized mouse models have provided us with valuable information on human immunity. Recent developments in recipient mouse strains and engraftment protocols have resulted in models with high level of de novo formation of human immune cells. Here we describe the development and improvements of humaniz...
The Authors regret that in the original abstract, Dr. Christie Orschell was listed as second author which incorrect. correct Author line is shown above. 3161 – CELLULAR AND MOLECULAR EFFECTS OF DMPGE₂ RADIOMITIGATION IN MOUSE HUMAN BONE MARROW CELLS VIVO USING C57BL/6 HUMANIZED NSG MODELS ACUTE RADIATION SYNDROMEExperimental HematologyVol. 111PreviewThe hematopoietic system highly sensitive to ...
Introduction: Pembrolizumab (Keytruda®) is a potent and selective humanized monoclonal immunoglobulin antibody that blocks programmed cell death-1 on T cells, augmenting the antitumor immune response. an approved adjuvant therapy for treating metastatic melanoma.
Humanized mice are emerging as an alternative model system to well-established non-human primate (NHP) models for studying human immunodeficiency virus (HIV)-1 biology and pathogenesis. Although both NHP and humanized mice have their own strengths and could never truly reflect the complex human immune system and biology, there are several advantages of using the humanized mice in terms of using...
I-8: A Preliminary Report on Production of Organ Deficient Goats at Royan Institute of Biotechnology
Shortage of transplantable organs available for people with endstage diseases has become goal of scientific project worldwide to find new approaches for providing the needed organs. These projects have mainly focused on complementation of pig embryo genetically manipulated or designed to produce an organ deficient embryo. Considering the fact that pig is not the common domestic animal in Middle...
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