A straightforward synthesis of novel, 2-heterocyclyl polyhydroxylated pyrrolidines is described. Stereocontrolled additions of nucleophiles to cyclic nitrones generated the corresponding 2,3-trans adducts, allowing the synthesis of the corresponding pyrrolidines via key intermediates bearing an alkyne and a nitrile oxide. Three hybrid systems, including a pyrrolidine with two isoxazoles and one...

1 This paper reports a performance comparison between traditional (linear PID controller) and cognitive methods (neural networks, genetic algorithms and simulated annealing) applied to the problem of real-time control. A one-axis magnetic bearing is considered as a case study and cognitive methods have been successfully applied to its control. Comparisons are made using a real test setup. It is...

We discuss the conductance of a molecular bridge between mesoscopic electrodes supporting low-dimensional transport and bearing an internal structure. As an example for such nanoelectrodes we assume semi-infinite (carbon) nanotubes. In the Landauer scattering matrix approach, we show that the conductance of this hybrid is very sensitive to the geometry of the contact, unlike the usual behavior ...

Ferromagnetic carbon-coated cobalt nanoparticles have been ligated by a covalent or non-covalent strategy with dendrons or polymers bearing amino-, hydroxy- or polyether-functionalities, aiming at synthesizing materials that are dispersible in aqueous solutions, being a prerequisite for applications in biomedicine. Most efficiently for this purpose proved to be a covalently anchored polyethylen...

The nature of soil varies horizontally as well vertically, owing to the process formation soil. Thus, ensuring safe design geotechnical structures has been a major challenge. In shallow foundations, conducting field tests is expensive and time-consuming often conducted on significantly scaled-down models. Empirical models, too, have found be least reliable in literature. study proposes AI-based...

This paper investigates a novel integrated AC–DC hybrid magnetic bearing (HMB) to reduce the volume, weight, manufacturing, and operation cost of suspension motors. Two radial MBs an axial MB are with proposed HMB. The five-degree-of-freedom (5-DOF) is realized in one unit. axially polarized permanent magnets provide bias fluxes. First, HMB structure mechanism introduced. Second, based on metho...

Hybrid cell line 108CC5, obtained by fusion of N18TG2 mouse neuroblastoma and C6BU1 rat glioma lines, was injected intracranially or s.c. into nude mice. The tissues of the resultant intracranial and s.c. tumors were processed for light, phase, and electron microscopy. For comparison, the tumors induced by inoculation of the parent lines in the respective animal hosts were also studied. Histolo...

Calcium phosphate nanoparticles are safe and effective delivery vehicles for small interfering RNA (siRNA), as a result of their excellent biocompatibility. In this work, mPEG-PE (polyethylene glycol-L-α-phosphatidylethanolamine) was synthesized and used to prepare nanoparticles composed of mPEG-PE and calcium phosphate for siRNA delivery. Calcium phosphate and mPEG-PE formed the stable hybrid ...