نتایج جستجو برای: hydantoin derivatives
تعداد نتایج: 105363 فیلتر نتایج به سال:
BACKGROUND Many effective innovations and interventions are never effectively scaled up. Implementation research (IR) has the promise of supporting scale-up through enabling rapid learning about the intervention and its fit with the context in which it is implemented. We integrate conceptual frameworks addressing different dimensions of scaling up (specifically, the attributes of the service or...
This paper presents a method for synthesis and cytotoxicity of new platinum(II) complexes of (9'-fluorene)-spiro-5-hydantoin (L1) and (9'-fluorene)-spiro-5-(2-thiohydantoin) (L2). The new obtained complexes were studied by elemental analysis: ultraviolet-visible, attenuated total reflection Fourier transform infrared (ATR-FTIR), and 1H- and 13C-NMR for Pt(II) compounds and additionally Raman sp...
Phytochemical investigation of the cytotoxic fractions of fresh bulbs of Pancratium maritimum L. led to the isolation and structure identification of two new compounds, pancricin (1) and pancrichromone (4), together with four known compounds, including 2,4-dihydroxy-6-methoxy-3-methyl acetophenone (2), 5-formylfurfuryl acetate (3), 7-beta-D-glucosyloxy-5-hydroxy-2-methylchromone (5), and ethyl-...
Transient precursor states are often experimentally observed for molecules adsorbing on surfaces. However, such precursor states are typically rather short-lived, quickly yielding to more stable adsorption configurations. Here we employ first-principles calculations to systematically explore the interaction mechanism for benzene derivatives on metal surfaces, enabling us to selectively tune the...
The aryl hydantoin 1 (Ro 13-3978) was identified in the early 1980s as a promising antischistosomal lead compound. However, this series of aryl hydantoins produced antiandrogenic side effects in the host, a not unexpected outcome given their close structural similarity to the antiandrogenic drug nilutamide. Building on the known SAR of this compound series, we now describe a number of analogs o...
Based on the 40-year follow-up of the Framingham Heart Study (FHS), we used logistic regression models to demonstrate that different designs of an observational study may lead to different results about the association between BMI and all-cause mortality. We also used dynamic survival models to capture the time-varying relationships between BMI and mortality in FHS. The results consistently sho...
Ammonium nitrate (AN) is widely used in fertilizers, civilian explosives and military explosives. Due to crystalline phase transitions and density changes of AN in the ambient conditions, its usage as oxidizer in solid propellants has some limitations as compared to ammonium perchlorate (AP). Several methods have been introduced to overcome these problems. In the present paper, the phase transi...
An< accurate, stable and very fast corner finder (for feature based vision) has been developed', based on a novel definition of corners, using:no image derivatives. This note describes the algorithm and the results obtained from its use.
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