Porous and granular hydroxylapatite (HAP) was implanted in bone defects resulting from oral surgery in 21 patients and from periodontal disease in 14 patients. Excellent results were obtained, the overall clinical usefulness being 91.4%. HAP leakage after implantation was observed in a small number of cases; however, there was almost no wound infection or failure to heal. A series of x-rays con...

Hydroxylapatite – Ca5(PO4)3(OH) – is the main mineral in bones, giving them their compressive strength, and, as found in nature, is often called phosphate rock. Phosphate rock is commercial mined for its phosphorus, for use in fertilizers and other purposes. Its formation is sometimes used to remove phosphorus from wastewaters, including manures. It is often also known as hydroxyapatite (that i...

Although no amine oxidase could be detected in crude extracts, the enzyme has been purified to apparent homogeneity from Hordeum vulgare seedlings using ammonium sulfate precipitation and chromatography on DEAE cellulose, Hydroxylapatite, and Sephadex G200 columns. Gel filtration experiments indicate a molecular weight of about 150,000. The pH optimum of the enzyme was found to be 7.5 in potass...

We have previously found that human breast cancer cells in tissue culture contain estrogen receptor in their nuclei despite the absence of estrogen. We have now investigated solid human breast cancer biopsies and find that proteolytic activities in extracts from the nuclear pellets of these biopsies interfere with or prevent the measurement of nuclear estrogen receptor when the protamine assay ...

The peptidoglycan synthetic enzymes can be dissociated with cholate and LiCl into components with mobilities on a gel filtration column in the same ranges as bovine serum albumin. The active enzymes can be separated further from the lipids necessary for synthesis by precipitation with ammonium sulfate. The needed lipids stable to hydrolysis with base. A protein needed for peptidoglycan polymeri...