Indium-111 ("'In) bound to 8-hydroxyquinoline can be used to label platelets without impairing their ability to participate in active thrombosis. The purpose of this study was to identify intracardiac thrombi using "'In platelet scintigraphy. Twenty-nine patients were studied. Twenty-one had discrete left ventricular aneurysms (group 1). The remaining eight patients (group 2) had normal or mini...

An electronically segmented amphiphile was created by conjugating two π-functional units hydroxyquinoline and naphthalenediimide (HQ/NDI) for the first time. The differential electrostatic potential of the π-surfaces, H-bonding units, etc. trigger a manifold response and direct the assembly of a unique collection of seven diverse nano-architectures. Chiral assembly, distinct classes of fibers, ...

The respiratory-chain inhibitor 2-n-heptyl-4-hydroxyquinoline N-oxide catalyses transmembrane proton transport driven by a pH gradient in isolated rat liver mitochondria. This effect explains the apparent blockade of net proton translocation by this compound in mitochondria respiring with ferrocyanide as described by Papa, Lorusso, Guerrieri, Boffoli, Izzo & Capuano [(1977) in Bioenergetics of ...

RAISED serum levels ofprotein-bound iodine (PBI) in patients with normal thyroid function have been observed on many occasions after oral treatment with 5-chloro-7-iodo-8-hydroxyquinoline (iodochlorhydroxyquinoline, clioquinol, Enterovioform) (Thoren, 1960; Levin, Josephson & Grtnewald, 1966; Sonksen et al., 1968). It is less well appreciated that clioquinol administered topically can be absorb...

A series of fluorescent sensors based on 8-hydroxyquinoline dansylate as core and dendritic PAMAM as shell were synthesized. Their fluorescence characteristic and fluorescent sensing behavior toward metal ions were studied in water/methanol (1: 1, v/v). The sensors exhibit good selectivity and sensitivity for Fe(3+) ion and to some extent for Cr(3+) ion. The third generation dendrimer has the b...

In the course of a comprehensive survey of the chemotherapy of amcebiasis, Leake (1932) studied the properties of iodochlorhydroxyquinoline (enterovioform or vioform, N.N.R.) in comparison to chiniofon, N.N.R. (sodium iodohydroxyquinoline sulphonate) and certain other derivatives of hydroxyquinoline from the standpoint of oral toxicity in guinea-pigs and cats, amcebicidal action in vitro, and b...

Indium-111 ("'In) bound to 8-hydroxyquinoline can be used to label platelets without impairing their ability to participate in active thrombosis. The purpose of this study was to identify intracardiac thrombi using "'In platelet scintigraphy. Twenty-nine patients were studied. Twenty-one had discrete left ventricular aneurysms (group 1). The remaining eight patients (group 2) had normal or mini...

We synthesized new electroluminescence materials [(1,10-phenanthroline)(8-hydroxyquinoline)] Zn(phen)q and investigated their electron transport properties. We used Zn(phen)q and Alq3 for the conductive materials and measured their electron transport properties as a function of the organic layer thickness. The difference between Zn(phen)q and Alq3 as electron transporting materials suggests tha...

A series of 5-dialkyl(aryl)aminomethyl-8-hydroxyquinoline dansylates were synthesized and their fluoroionophoric properties toward representative alkali ions, alkaline earth ions and transition metal ions were investigated. Among the selected ions, Fe3+ caused considerable quenching of the fluorescence, while Cr3+ caused quenching to some extent. The absence of any significant fluorescence quen...