objectives: it is important to recognize any risk factors for the development of injuries in the athletic population. the aim of this study was to investigate the association between joint hyper mobility and low back pain in iranian hyper mobile and non-hyper mobile athletes. methods: 50 athletic patients with low back pain (age=23.20±12.79 years) and 51 healthy athletes (age=24.28±13.70) from ...

BACKGROUND Mutations in the dedicator of cytokinesis 8 gene (DOCK8) cause a combined primary immunodeficiency syndrome that is characterized by elevated serum IgE levels, depressed IgM levels, eosinophilia, sinopulmonary infections, cutaneous viral infections, and lymphopenia. Many patients with DOCK8 deficiency were previously thought to have a variant of Job's syndrome. Distinguishing between...

background: hyper ige syndrome (hies) is a rare primary immune deficiency, described as job`s syndrome characterized by increased serum levels of ige, eczema, recurrent cutaneous and pulmonary infections. in this paper, we presented a case of hyper ige syndrome.case presentation: a 16-year-old iranian boy presented with a one year history of skin lesions in knees and elbows was diagnosed of pso...

The C'1a-fixing properties of purified rabbit IgM anti-benzenearsonate antibody were determined. When tested with sheep erythrocytes to which hapten had been coupled by diazo linkage, the number of C'1a molecules fixed was 21% of the number of IgM antibody molecules bound to the erythrocyte surface. This was not due to loss of C'1a-fixing capacity during the purification procedure. Preparative ...

Recent work suggests that IgG and IgM from nonimmune human serum (natural antibodies) bind to the surface of Plasmodium falciparum-infected erythrocytes and contribute to rosette formation by stabilizing the interaction between infected and uninfected erythrocytes. Here we show, in both laboratory clones and field isolates, that only IgM but not IgG is detected on the surface of infected cells....