نتایج جستجو برای: hypercholesterolaemia
تعداد نتایج: 1774 فیلتر نتایج به سال:
PURPOSE OF REVIEW Familial hypercholesterolaemia (FH) is an inherited disorder of low-density lipoprotein cholesterol (LDL-C) which is characterised by a raised cholesterol level from birth and a high risk of premature coronary heart disease. In this paper, we review the genetic basis of FH and its impact on the clinical presentation. RECENT FINDINGS Mutations in any of three genes (LDLR, APO...
A 77-year-old man presented to our neurology clinic reporting short episodes of unsteadiness followed by loss consciousness brought on standing from a sitting position. The problem had been present for 2 weeks and led frequent falls. He history hypertension—treated with amlodipine, atenolol, perindopril—and hypercholesterolaemia—treated ezetimibe. was non-smoker.
BACKGROUND In patients with coronary artery disease (CAD), the site and extent of coronary artery involvement in terms of proximal versus distal stenosis and multi- versus single-vessel disease have a crucial effect on patients' outcome. This study was designed to evaluate the relationship between cardiovascular risk factors and the site and extent of coronary artery involvement. METHODS In t...
OBJECTIVE To determine the efficacy of statin treatment on risk of coronary heart disease in patients with familial hypercholesterolaemia. DESIGN Cohort study with a mean follow-up of 8.5 years. SETTING 27 outpatient lipid clinics. SUBJECTS 2146 patients with familial hypercholesterolaemia without prevalent coronary heart disease before 1 January 1990. MAIN OUTCOME MEASURES Risk of coro...
The effects of hypercholesterolaemia on testicular endocrine and exocrine function were evaluated. The influence of hypercholesterolaemia on sperm quality, quantity, and fertilizing potential was also determined. Ten mature rabbits (group A) were fed chow containing 3% cholesterol for 12 weeks. Ten control rabbits (group B) were fed normal chow for the same period. At the end of the experimenta...
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