Background: Prolactin, a neurohormone, can act as a stimulator of immunity in a number of autoimmune diseases and its high levels have been shown in these diseases. Objective: This study was designed to discover the possible role of prolactin in autoimmune blistering skin diseases. The main goal was to compare the serum prolactin levels and the frequency of hyperprolactinemia in autoimmune skin...

To the Editor: Quetiapine is an atypical antipsychotic agent with less propensity than other atypical antipsychotics to induce antipsychotic-associated hyperprolactinemia in standard recommended therapeutic dosages, and when it does induce the condition at all, the rise in serum prolactin level is only transient. Accordingly, quetiapine has been recommended as an alternative in patients who dev...

All the studies on hyperprolactinemia should not forget to consider the possible presence of macroprolactinemia Pierluigi Amadori, Costantino Dilberis and Alberto Marcolla Outpatient Endocrinology Service, Azienda Provinciale per i Servizi Sanitari, Trento, Italy, Laboratory of Clinical Analysis, S. Camillo Hospital, Trento, Italy and Clinical Chemistry Unit, Azienda Provinciale per i Servizi S...

The symptoms of hyperprolactinemia in women mainly result from changes in the release of gonadotropins and the consequent repercussions on ovarian function. Metoclopramide is a hyperprolactinemic drug that is used as an antiemetic agent. In female mice, metoclopramide-induced hyperprolactinemia causes changes in the reproductive system, mainly in ovarian function and the endometrium. While ther...

A female hemodialysis patient with galactorrhea due to hyperprolactinemia was treated with different dialysis modalities to assess the effect on prolactin levels. A single session of both high-flux hemodialysis and hemodiafiltration resulted in decreased prolactin levels (16,6% and 77,2%, resp.). However, baseline prolactin levels measured immediately before the next dialysis session did not ch...