burns account for a significant proportion of injuries, and of these the face, neck, and anterior torso are commonly affected. burn scars remain a lasting reminder of the insult both for the patient and the outside world. there is little doubt that the change in appearance and the limitation imposed by a burn scar contribute to negative body image. treatment of hypertrophic scars in the neck ha...

Pathological scarring at the present stage does not have a clear pathogenetic justification, it is characterized by unpredictability and constant growth of keloid scars, absence regression for many years reasonable treatment. Despite fact that there possibility extirpation excess tissue, almost impossible to remove scars without recurrence. The paper presents phenotyping data in structure cellu...

BACKGROUND Abnormal (keloid and hypertrophic) scars are a significant affliction with no satisfactory single modality therapy to-date. Available options are often ineffective, painful, potentially hazardous, and require healthcare personnel involvement. Herein a self-administered microneedle device based on drug-free physical contact for inhibiting abnormal scars is reported. Its therapeutic ac...

GENERAL PURPOSE To provide information about the clinical presentation of hypertrophic scars and keloids based on their varied structural components. TARGET AUDIENCE This continuing education activity is intended for physicians, physician assistants, nurse practitioners, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES After completing this continuing educati...

Intralesional steroid injections are the standard treatment for hypertrophic scars and keloids. The procedure is, however, quite painful and is unpopular with patients because of this. Topical application of anesthetic creams, such as Ametop gel (tetracaine) and EMLA cream (lidocaine and prilocaine), has limited efficacy because of poor drug penetration. The onset of the analgesic effect is als...

The use of five fluorouracil (5 FU) as antifibrotic started in the 1960s, in hands of ophthalmologists, to prevent adherence after glaucoma and pterigion surgery. In 1999 Fitzpatric presented his experience in keloids and hypertrophic scars, making a great contribution to their treatment. Fibroblasts main function is collagen synthesis; in vicious scar the amount of collagen is normal, but what...