OBJECTIVES To determine whether subjective poor sleep prospectively increases functional limitations and incident disability in a national sample of adults living in the United States. DESIGN Prospective cohort. SETTING Longitudinal Survey of Midlife Development in the United States (MIDUS). PARTICIPANTS Young, middle-aged, and older men and women (aged 24-75) surveyed in 1995/96 (MIDUS 1...

INTRODUCTION Falls in elderly women producing fractures are a public health problem that could be largely preventable. The aim of this study was to determine the effect of visual impairment on functional status, falls and fractures in women. MATERIAL AND METHODS We examined 623 women aged ≥ 55 years in order to assess the association between visual status and functional status and the risk of...

OBJECTIVES We attempt to understand the influence of residential mobility on changes in objective activity of daily living (ADL) and instrumental ADL (IADL) limitations, while taking into account the subjective reason for the move. METHODS We examine noninstitutionalized adults aged 70 and older who are in the Longitudinal Study of Aging. We use bivariate regression to identify differences be...

AIM Determine whether patients with Alzheimer's disease demonstrating functional and cognitive decline, following 24-48 weeks of open-label treatment with 9.5 mg/24 h (10 cm(2)) rivastigmine patch, benefit from a dose increase in a double-blind (DB) comparative trial of two patch doses. METHODS Patients meeting prespecified decline criteria were randomized to receive 9.5 or 13.3 mg/24 h (15 c...

PURPOSE This study examined the relation of dual and single sensory impairments, within the context of cognitive function, by using the framework of everyday competence in terms of the probability of difficulty with specific personal and instrumental activities of daily living (ADLs and IADLs, respectively). DESIGN AND METHODS The Longitudinal Study on Aging, composed of individuals aged 70 a...

BACKGROUND Caregivers play a major role in the care of patients with dementia and are themselves at higher risk of disease. OBJECTIVES We investigate which factors are associated with caregivers burden of outpatients visiting a memory clinic and how functional autonomy and behavioral and psychological symptoms can influence caregiver burden. METHODS The study population was chosen from outp...

OBJECTIVES To compare differences in the functional outcomes experienced by patients cared for in Hospital at Home (HaH) and traditional acute hospital care. DESIGN Survey questionnaire of participants in a prospective nonrandomized clinical trial. SETTING Three Medicare managed care health systems and a Veterans Affairs Medical Center. PARTICIPANTS Two hundred fourteen community-dwelling...

OBJECTIVE To assess the effects of mobility loss on instrumental activities of daily living (IADL) and socioeconomic status in multiple sclerosis (MS) patients. METHODS Participants were active registrants in the North American Research Committee on Multiple Sclerosis registry completing the Fall 2006 (IADL analysis, n = 10,396) or Spring 2007 (socioeconomic analysis, n = 8180) surveys. Cross...

The objective of the present study was to determine the potential long-term impact of dietary habits on age-related decline among 4809 elderly women (born between 1925 and 1930) in the 'Etude Epidémiologique de Femmes de la Mutuelle Générale de l'Education Nationale' (E3N) study, a French epidemiological cohort. In 1993, an extensive diet history self-administered questionnaire was sent to all ...

Objectives The ability of older adults to live independently is often assessed with a battery of questions known as Instrumental Activities of Daily Living (IADLs). Many of these questions query the difficulty conducting household activities that have been predominantly conducted by women (e.g., the ability to prepare a meal), especially for cohorts now in old age. Although previous research ha...