OBJECTIVE To identify and compare clinical and neuroimaging predictors of primary lobar intracerebral hemorrhage (ICH) recurrence, assessing their relative contributions to recurrent ICH. METHODS Subjects were consecutive survivors of primary ICH drawn from a single-center prospective cohort study. Baseline clinical, imaging, and laboratory data were collected. Survivors were followed prospec...

Background and Purpose—Intracerebral hemorrhage (ICH) constitutes 10% to 15% of all strokes and remains without a treatment of proven benefit. Despite several existing outcome prediction models for ICH, there is no standard clinical grading scale for ICH analogous to those for traumatic brain injury, subarachnoid hemorrhage, or ischemic stroke. Methods—Records of all patients with acute ICH pre...

BACKGROUND Primary intracerebral hemorrhage (ICH) occurs more commonly in Taiwan than in other western countries. Recurrence of primary ICH after a first episode is not rare. The purpose of this study is to investigate the incidence, risk factors, and prognosis of recurrent primary ICH. METHODS From the stroke registration data of Kaohsiung Veterans General Hospital (KSVGH), all patients admi...

We investigated the frequency and characteristics of intracranial hemorrhage (ICH), the factors associated with the risk of ICH, and outcomes post-ICH overall and by randomized treatment. We identified patients with ICH from the overall trial population enrolled in the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation trial who received ≥1 dose of the study...

background: intracerebral  hemorrhage (ich) is the  most fatal subtype  of stroke.  despite  limited effective therapy, there  is no  accepted clinical grading  scale to  predict  in- hospital  mortality,  especially  in developing  nations.  the purpose  of this study was to assess the  predictors  of in- hospital mortality among a sample of iranian patients  with spontaneous ich for use at th...

intra-cerebral hemorrhage (ich) is a particularly severe type of stroke accounting for 10–15 % of all strokes and is associated with a mortality rate of 30–50%. neuroinflammation contributes to ich-induced secondary brain injury and understanding the mechanisms causing neuroinflammation can be helpful to find new treatments of ich. recent studies demonstrated that toll like receptor 2 (tlr2) fo...

Fish infected with Ich may have white specks on their skin as though they were sprinkled with salt (Fig. 1). Because of this appearance, Ich is sometimes called white spot disease. The skin of the fish may also look bumpy. Mature forms of the parasite are large (up to 1 mm or 1/32 inch across) and can be seen without magnification. Ich often causes the fish to have large amounts of mucus slough...

PURPOSE A simple stability-indicating RP-HPLC assay method was developed and validated for quantitative determination of Chloramphenicol, Dexamethasone Sodium Phosphate and Tetrahydrozoline Hydrochloride in ophthalmic solution in the presence of 2-amino-1-(4-nitrophenyl)propane-1,3-diol, a degradation product of Chloramphenicol, and Dexamethasone, a degradation product of Dexamethasone Sodium P...

Due diligence is a vital activity in the acquisition or the in-licensing of pharmaceutical compounds for market commercialization. Pharmaceutical product due diligence is a detailed investigation of the chemistry, manufacturing, and controls (CMC) information associated with a drug product. The investigation provides assurance that a given compound will meet the requisite technical and quality ...

Submit Manuscript | http://medcraveonline.com J Neurol Stroke 2016, 4(1): 00119 It is well recognized that treatment of hypertension is critical in the early management of ICH, aneurysmal SAH, and RPLS. This creates a dilemma in that aggressive hypertension management can place a patient at risk of ischemia due to cerebral hypoperfusion. There is no specific blood pressure control and CV manage...