نتایج جستجو برای: idarubicin
تعداد نتایج: 767 فیلتر نتایج به سال:
In the Arabidopsis thaliana genome, over 1000 putative genes encoding small, presumably secreted, signalling peptides can be recognized. However, a major obstacle in identifying the function of genes encoding small signalling peptides is the limited number of available loss-of-function mutants. To overcome this, a promising new tool, antagonistic peptide technology, was recently developed. Here...
Venirepersons's attitudes toward the insanity defense: developing, refining, and validating a scale.
Given the prevalence and predictive strength of negative attitudes toward the insanity defense, we conducted three studies with 426 venirepersons to develop an understanding and a measure of public attitudes toward the insanity defense. In these studies, we developed, iteratively refined, and cross-validated the insanity defense attitude-revised (IDA-R) scale. The results suggest that IDAs are ...
There is no effective treatment for recurrent glioblastoma (GB) when temozolomide-based radiochemotherapy fails. In theory, intra-arterial (IA) delivery of cytotoxic agents could achieve higher drug concentrations in tumors compared to intravenous injection. Moreover, choosing a highly lipid-soluble drug could make the most of the first-pass effect. Here, we evaluated idarubicin (IDA), a lipoph...
Shigeki Ohtake,1 Shuichi Miyawaki,2 Hiroyuki Fujita,3 Hitoshi Kiyoi,4 Katsuji Shinagawa,5 Noriko Usui,6 Hirokazu Okumura,7 Koichi Miyamura,8 Chiaki Nakaseko,9 Yasushi Miyazaki,10 Atsushi Fujieda,11 Tadashi Nagai,12 Takahisa Yamane,13 Masafumi Taniwaki,14 Masatomo Takahashi,15 Fumiharu Yagasaki,16 Yukihiko Kimura,17 Norio Asou,18 Hisashi Sakamaki,19 Hiroshi Handa,20 Sumihisa Honda,21 Kazunori Oh...
The involvement of central nervous system is rare in acute promyelocytic leukemia (APL). We report a APL patient of a 41 yr-old Korean male who presented with fever and petechia. Complete molecular remission was achieved with all-trans retinoic acid (ATRA), idarubicin, and cytarabine. Ten months later, he complained of a mild headache. The results of the physical examination and the complete bl...
The meningeal involvement is rare in acute promyelocytic leukemia. We experienced a 39-year-old woman who achieved complete remission with all-trans retinoic acid, idarubicin and cytarabine therapy. Several months later, she complained of non-specific headache. Her complete blood cell count was normal, but magnetic resonance image of brain revealed focal meningeal enhancement and cerebrospinal ...
Adults with disabilities disproportionally experience poverty. We examine one novel strategy to promote economic well-being among adults with disabilities living in or near poverty, namely Individual Development Accounts (IDAs). IDAs are designed to help individuals save money and subsequently accumulate assets. Although adults with disabilities account for the majority of IDA participants, sca...
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