BACKGROUND AND PURPOSE Destructive lesions of the sinonasal tract, lacking a discernible etiology and referred to as midline destructive disease, have been pathologically classified in accordance with a variety of confusing terms. Development of new pathologic concepts and immunohistochemical techniques has provided a fresh understanding of these lesions, and, as a result, they can be unified i...

Idiopathic granulomatous inflammation is regarded as a histopathologic variant of an orbital pseudotumor and has a similar clinical presentation and treatment. However, the differential diagnosis including sarcoidosis, Wegener's granulomatosis, trauma, and infection must be ruled out. We present a 77-year-old man with a biopsy-proven lacrimal gland granulomatous inflammation of an unknown origi...

Idiopathic granulomatous mastitis is a relatively rare chronic inflammatory breast disease often mistaken for more common breast disorders, breast abscess or infectious mastitis, and can mimic inflammatory breast cancer.1,2 Since it was first described in 1972 by Kessler and Wolloch3, there have been only 541 cases reported worldwide as shown in a 2011 review article.4 Most patients are women o...

Hypertrophic pachymeningitis (HP) is an inflammatory condition in which the dura mater of the cranium or spine becomes thickened, leading to symptoms that result from mass effect, nerve compression, or vascular compromise. The differential diagnosis of HP includes immune-mediated conditions such as rheumatoid arthritis and vasculitis, malignancies, and infections. Many times, no diagnosis is re...

Problem statement: Granulomatous Lobular Mastitis (GLM) or autoimmune mastitis is a rare and benign disease which, except one case reported in an old man, is usually seen during pregnancy or lactation period. This disease was described for the first time by Kessler. Approach: Our case is a 34 year-old woman who has a child with a history of using OCP that primary complaint was swelling, heat an...

Etiological classification of diabetes insipidus is as follows. 1. Central Diabetes Insipidus (CDI) A. Idiopathic B. Familial C. Structural Causes i. Congenital: Septo-optic dysplasia Tuber cinereum Hamartoma ii. Traumatic: Iatrogenic, head trauma iii. Inflammatory: Tuberculous Meningitis Sarcoidosis Wegener’s granulomatosis Lymphocytic Hypophysitis iv. Neoplastic: a. Pediatric: Hypothalamic gl...

LEGGATT, P. 0. and WALTON, E. W. (1956): Wegener's Granulomatosis, Thorax, II, 94. MooRE, P. M., BEARD, E. E., THOBURN, T. W., and WILLIAMs, H. L. (I951): Idiopathic (lethal) Granuloma of Mid-line Facial Tissues Treated with Cortisone Report of a Case, Laryngoscope (St. Louis), 6i, 320. WALTON, E. W. (1958): Giant Cell Granuloma of the Respiratory Tract (Wegener's Granulomatosis), Brit. med. 7....

OBJECTIVES/HYPOTHESIS To evaluate the endoscopic surgical management of adult subglottic stenosis and describe treatment outcomes. STUDY DESIGN Retrospective review. METHODS Ten-year review of adult patients with subglottic stenosis. RESULTS Ninety-two adults (23 male, 69 female) with subglottic stenosis underwent 247 endoscopic dilations between 2001 and 2010. The mean age was 48 years a...

OBJECTIVE To study the characteristics of inflammatory breast aspirate by Fine Needle Aspiration, performed by pathologist. METHODS Inflammatory breast aspirates reported at two hospitals in Taif area (King Abdul Aziz Specialist Hospital and Al Hada Armed Forces Hospital, Taif, Kingdom of Saudi Arabia (KSA) from January 2000 till September 2007 were reviewed. The cytopathology reports, slides...