This paper gives a kinetic analysis of the K(+)-selective outward-rectifier (IK,out) in the plasma membrane of Arabidopsis thaliana mesophyll cells in terms of the Hodgkin-Huxley formalism. We compared the kinetic characteristics of IK,out in Arabidopsis with IK,out channels in three other plant species that were subjected to a similar analysis: tobacco suspension cells, Vicia faba guard cells ...

Light activation of Drosophila photoreceptors leads to the generation of a depolarizing receptor potential via opening of transient receptor potential and transient receptor potential-like cationic channels. Counteracting the light-activated depolarizing current are two voltage-gated K+ conductances, IA and IK, that are expressed in these sensory neurons. Here we show that Drosophila photorecep...

Ikaros, a zinc finger-containing DNA-binding protein, is required for normal lymphocyte development. Germ-line mutant mice that express only non-DNA binding dominant-negative "leukemogenic" Ikaros isoforms lacking critical NH2-terminal zinc fingers develop an aggressive form of T-cell leukemia. We studied Ikaros gene expression in leukemic cells from 18 children with T-cell acute lymphoblastic ...

autumn planting of sugar beet as compared to its spring cultivation demands less application of water in semi-arid region such as iran. therefore, cultivation of sugar beet in autumn is considered as a better choice to be benefited from autumn and winter precipitation and escaping from water deficit crises. in two areas of aran-o-bidgol, esfahan (ae) and izeh, khuzestan (ik), two independent ex...

RATIONALE Electrical conduction through gap junction channels between endothelial cells of resistance vessels is integral to blood flow control. Small and intermediate-conductance Ca(2+)-activated K(+) channels (SK(Ca)/IK(Ca)) initiate electrical signals in endothelial cells, but it is unknown whether SK(Ca)/IK(Ca) activation alters signal transmission along the endothelium. OBJECTIVE We test...

Rat superior cervical ganglion (SCG) neurons express low-threshold noninactivating M-type potassium channels (IK(M)), which can be inhibited by activation of M1 muscarinic receptors. This inhibition occurs via pertussis toxin-insensitive G-proteins belonging to the Galphaq family (Caulfield et al., 1994 ). We have used DNA plasmids encoding antisense sequences against the 3' untranslated region...

1. The development of Ca2+ and K+ currents was studied in ascidian muscle cells at twelve embryonic stages from gastrulation to the mature cell, a period of 24 h. A high degree of co-ordination occurs between the development of the inwardly rectifying K+ current (IK(IR)), which sets the resting potential, and Ca2+ and outward K+ currents, which determine action potential waveform. 2. At neurula...

Dutta AK, Khimji A, Sathe M, Kresge C, Parameswara V, Esser V, Rockey DC, Feranchak AP. Identification and functional characterization of the intermediate-conductance Ca -activated K channel (IK-1) in biliary epithelium. Am J Physiol Gastrointest Liver Physiol 297: G1009–G1018, 2009. First published September 17, 2009; doi:10.1152/ajpgi.00223.2009.—In the liver, adenosine triphosphate (ATP) is ...

(using the restricted product topology ensures that a 7→ a−1 is continuous, which is not true of the subspace topology). As a topological group, IK is locally compact and Hausdorff. The multiplicative group K× is canonically embedded as a discrete subgroup of IK via the diagonal map x 7→ (x, x, x, . . .), and the idele class group is the quotient CK := IK/K, which is locally compact but not com...